{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:07:21Z","timestamp":1791821241831,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T00:00:00Z","timestamp":1613692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Proton beam radiation therapy (PBRT) has dosimetric advantages compared to photon radiation therapy for the treatment of major salivary gland tumors (MSGTs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with non\u2010metastatic MSGTs treated at a single proton therapy center from October 2013 to October 2018 were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010eight patients with MSGTs were included and the most common site and histology were the parotid gland (75.0%) and adenoid cystic carcinoma (22.1%), respectively. The 3\u2010year rates of locoregional control, progression\u2010free survival, and overall survival were 95.1% (95% CI: 89.9%\u2010100.0%), 80.7% (70.2%\u201092.7%), and 96.1% (95% CI: 90.9%\u2010100.0%), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a large cohort of MSGTs treated with PBRT, the rates of locoregional control were high in short\u2010term follow\u2010up and treatment was well tolerated.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.26563","type":"journal-article","created":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T01:27:20Z","timestamp":1613870840000},"page":"1056-1062","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Outcomes and prognostic factors of major salivary gland tumors treated with proton beam radiation therapy"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3921-480X","authenticated-orcid":false,"given":"Kaveh","family":"Zakeri","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huili","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Julie","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Romesser","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nader","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daphna","family":"Gelblum","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Sherman","sequence":"additional","affiliation":[{"name":"Department of Medicine Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5318-2571","authenticated-orcid":false,"given":"Lara","family":"Dunn","sequence":"additional","affiliation":[{"name":"Department of Medicine Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Boyle","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0400-2655","authenticated-orcid":false,"given":"C. 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