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The aim of the present study was to evaluate the demographic and clinicopathological features of these neoplasms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was conducted of cases diagnosed as benign CSTNs, with data collected from biopsy records. The chi\u2010square test was used. A <jats:italic>p<\/jats:italic>\u2010value &lt;0.05 was considered indicative of statistical significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 38\u2009119 specimens, 1066 (2.79%) were benign CSTNs: 369 fibroblastic\/myofibroblastic, 250 adipocytic, 179 vascular, 130 neural, 94 osseous\/cartilaginous, 19 muscular, and two fibrohistiocytic. Most patients were female (62.8%) and white\u2010skinned (45.8%). Mean age was 42\u2009years. The tongue (25.2%) was the most affected site for extraosseous neoplasms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study had the largest sample of benign oral and maxillofacial CSTNs. Although these tumors have similar clinical features, the characterization and differentiation detailed here may help clinicians with regards to the correct diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.26580","type":"journal-article","created":{"date-parts":[[2020,12,19]],"date-time":"2020-12-19T15:14:33Z","timestamp":1608390873000},"page":"1202-1212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Benign connective and soft\u2010tissue neoplasms of the oral and maxillofacial region: Cross\u2010sectional study of 1066 histopathological specimens"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7655-8666","authenticated-orcid":false,"given":"Adriana Aparecida Silva","family":"da Costa","sequence":"first","affiliation":[{"name":"Department of Oral Pathology and Surgery School of Dentistry, Universidade Federal de Minas Gerais  Belo Horizonte 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