{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:59:10Z","timestamp":1793041150916,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The objective was to determine the incidence of, and factors associated with contralateral neck failure (CNF) in oral tongue squamous cell carcinoma (OTSCC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients with OTSCC between 2007 and 2016 were included. The predefined policy of the contralateral neck included neck dissection (ND) where the primary tumor extended\/crossed midline or the contralateral neck was involved; and elective nodal irradiation (ENI) where the primary tumor was \u22641\u2009cm from midline\/2\u00a0cm from tip.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 258 patients. ND was ipsilateral 169 (66%) and bilateral 33 (13%). Fifty\u2010five patients (21%) received ENI to the undissected contralateral neck. CNF occurred in 19 patients (7%) and was similar by treatment received. Utilizing this approach, we observed higher rates of CNF with increasing N classification, perineural invasion, extracapsular extension, and depth of invasion \u22656\u2009mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Using our institutional policy of treatment to the contralateral neck, a low rate of CNF (\u226410%) was observed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.26671","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T12:32:20Z","timestamp":1615984340000},"page":"2024-2031","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Contralateral neck failure in oral tongue cancer: Outcomes from two centers using predefined treatment criteria"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6093-5164","authenticated-orcid":false,"given":"Cristian","family":"Udovicich","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Sir Peter MacCallum Department of Oncology The University of Melbourne  Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Daniell","sequence":"additional","affiliation":[{"name":"Head and Neck Tumour Stream, Department of Surgery, The Royal Melbourne Hospital The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Wiesenfeld","sequence":"additional","affiliation":[{"name":"Head and Neck Tumour Stream, Department of Surgery, The Royal Melbourne Hospital The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Bressel","sequence":"additional","affiliation":[{"name":"Centre for Biostatistics and Clinical Trials Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Rowe","sequence":"additional","affiliation":[{"name":"Head and Neck Tumour Stream, Department of Surgery, The Royal Melbourne Hospital The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenic","family":"Vital","sequence":"additional","affiliation":[{"name":"Head and Neck Tumour Stream, Department of Surgery, The Royal Melbourne Hospital The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karda","family":"Cavanagh","sequence":"additional","affiliation":[{"name":"Cancer Imaging Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest","family":"Lekgabe","sequence":"additional","affiliation":[{"name":"Department of Radiology The Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Wong","sequence":"additional","affiliation":[{"name":"Head and Neck Tumour Stream, Department of Surgery, The Royal Melbourne Hospital The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J. R.","family":"Magarey","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Department of Medical Education The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim A.","family":"Iseli","sequence":"additional","affiliation":[{"name":"Head and Neck Tumour Stream, Department of Surgery, The Royal Melbourne Hospital The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsien","family":"Fua","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Sir Peter MacCallum Department of Oncology The University of Melbourne  Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny","family":"Rischin","sequence":"additional","affiliation":[{"name":"Sir Peter MacCallum Department of Oncology The University of Melbourne  Victoria Australia"},{"name":"Department of Medical Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4268-3079","authenticated-orcid":false,"given":"Lachlan","family":"McDowell","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Sir Peter MacCallum Department of Oncology The University of Melbourne  Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/02841860600609768"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23183"},{"key":"e_1_2_7_4_1","unstructured":"National Cancer Institute. 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