{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T15:24:51Z","timestamp":1790954691189,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T00:00:00Z","timestamp":1617148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To determine whether virtual surgical planning and three\u2010dimensional printed cutting guides (3D\/VSP) improved radiographic bone union compared to conventional methods (CM) in fibula free flap (FFF) reconstruction of the mandibles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective study from the years 2000\u20132018 at a tertiary hospital. Osseous union was evaluated by a radiologist blinded to each patient's treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Two hundred sixty patients who underwent FFF tissue transfer, 28 with VSP and 3D cutting guides. Bony union was not achieved in 46 (20%) patients who underwent CM compared to 1 (4%) of patients with VSP and guides (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.036). FFF complication was significantly higher in CM with 87 patients (38%) compared to three patients (11%) in 3D\/VSP (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.005). Median time to bony union for patients who underwent CM was 1.4\u2009years compared to 0.8\u2009years in 3D\/VSP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>3D\/VSP reduced the rate of radiographic nonunion and flap\u2010related complications in FFF reconstruction for mandibular defects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.26688","type":"journal-article","created":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T03:18:51Z","timestamp":1617160731000},"page":"2342-2352","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Short and long\u2010term outcomes of\n                    <scp>three\u2010dimensional<\/scp>\n                    printed surgical guides and virtual surgical planning versus conventional methods for fibula free flap reconstruction of the mandible: Decreased nonunion and complication rates"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6425-6991","authenticated-orcid":false,"given":"Matthew M.","family":"May","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin M.","family":"Howe","sequence":"additional","affiliation":[{"name":"Department of Radiology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"O'Byrne","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Research Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy E.","family":"Alexander","sequence":"additional","affiliation":[{"name":"Anatomical Modeling Lab Mayo Clinic  Rochester Minnesota 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