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The most common initial diagnosis was mucoepidermoid carcinoma (<jats:italic>n<\/jats:italic> = 19) with SDC being the most common revised diagnosis (7\/19). Thirteen salivary gland carcinomas were initially diagnosed as benign entities, whereas five benign tumors were initially interpreted as carcinoma. The change in diagnosis was considered to be clinically significant in 65 (97%) cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Given their rarity, salivary gland neoplasms are prone to diagnostic inaccuracy and discrepancy. A constellation of histologic features and ancillary studies are useful in reaching the correct diagnosis, which can have significant clinical impacts.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.26719","type":"journal-article","created":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T11:53:33Z","timestamp":1619265213000},"page":"2497-2509","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Diagnostic discrepancy in second opinion reviews of primary epithelial neoplasms involving salivary gland: An 11\u2010year experience from a tertiary referral center focusing on useful pathologic approaches and potential clinical impacts"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4638-9835","authenticated-orcid":false,"given":"Bin","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Pathology Memorial Sloan\u2010Kettering Cancer Center  New York New York 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