{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T23:41:39Z","timestamp":1769384499084,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T00:00:00Z","timestamp":1624492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Lesions arising from the upper parapharyngeal space (UPPS) often involved the jugular foramen region (JFR), occasionally extending into the posterior cranial fossa. This study aims to investigate the surgical anatomy of the JFR and UPPS from the perspective of an expanded endoscopic approach (EEA), tracing the lower cranial nerves from their extracranial foramina to the UPPS. Six cadaveric specimens (12 sides) underwent a transpterygoid EEA to expose the JFR and UPPS. Distances from the medial pterygoid plate (MPP) to the internal carotid artery (ICA), hypoglossal canal (HC), and jugular tubercle (JT) were measured on anonymized Computed tomography angiography images previously obtained from 30 patients with pulsatile tinnitus. Full access to the JFR, and its medial, superior, and anterior aspects, could be adequately achieved via an EEA. Upon exiting the jugular foramen, the glossopharyngeal nerve courses posterior to the ICA, traveling inferiorly into the UPPS between ICA and IJV. The vagus nerve is in close proximity to the hypoglossal nerve traveling posterior to the ICA. The accessory nerve courses lateral to the vagus nerve, running posterior to the IJV. The minimal distances from the MPP to ICA, HC, and JT were 2.52\u2009\u00b1\u20090.34, 2.86\u2009\u00b1\u20090.36, and 3.18\u2009\u00b1\u20090.33\u2009cm, respectively. This anatomical study strongly suggests the feasibility of using an EEA to access to the medial, superior, and anterior aspects of the jugular foramen and the adjacent UPPS.<\/jats:p>","DOI":"10.1002\/hed.26781","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T09:43:49Z","timestamp":1624527829000},"page":"3225-3233","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Endonasal access to lower cranial nerves: From foramina to upper parapharyngeal space"],"prefix":"10.1002","volume":"43","author":[{"given":"Lifeng","family":"Li","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Beijing Tongren Hospital, Capital Medical University  Beijing China"},{"name":"Department of Otolaryngology\u2014Head and Neck Surgery The James Cancer Hospital, Wexner Medical Center, The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nyall R.","family":"London","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery The James Cancer Hospital, Wexner Medical Center, The Ohio State University  Columbus Ohio USA"},{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Johns Hopkins School of Medicine  Baltimore Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"Prevedello","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery The James Cancer Hospital, Wexner Medical Center, The Ohio State University  Columbus Ohio USA"},{"name":"Department of Neurological Surgery The James Cancer Hospital, Wexner Medical Center, The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo L.","family":"Carrau","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery The James Cancer Hospital, Wexner Medical Center, The Ohio State University  Columbus Ohio USA"},{"name":"Department of Neurological Surgery The James Cancer Hospital, Wexner Medical Center, The Ohio State University  Columbus Ohio 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