{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:25:36Z","timestamp":1790904336549,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,7,17]],"date-time":"2021-07-17T00:00:00Z","timestamp":1626480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Extramedullary plasmacytomas are tumors that develop from plasma cells and rarely express anaplastic features. To our knowledge, there have only been three reported cases of anaplastic plasmacytomas of the sinonasal tract in the English literature. We detail the fourth case.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A 70\u2010year\u2010old male was seen with a 4\u2010month history of nasal congestion, bloody mucous, and left sided nasal obstruction. On positron emission tomography\/computed tomography, the lesion was FDG\u2010avid with an SUV<jats:sub>max<\/jats:sub> of 25.1. A biopsy of the lesion and subsequent immunohistochemical staining confirmed the diagnosis of an anaplastic plasmacytoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patient is undergoing a 5\u2010week course of curative\u2010intent radiation therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Extramedullary plasmacytomas with anaplastic features are very rare. We highlight the value of thorough histopathological review and detailed immunostains to arrive at a diagnosis of anaplastic extramedullary plasmacytoma.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.26818","type":"journal-article","created":{"date-parts":[[2021,7,17]],"date-time":"2021-07-17T09:38:39Z","timestamp":1626514719000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Rare case of anaplastic plasmacytoma in the sinonasal tract"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2094-475X","authenticated-orcid":false,"given":"Monica H.","family":"Xing","sequence":"first","affiliation":[{"name":"The Thyroid, Head and Neck Cancer (THANC) Foundation  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2611-6418","authenticated-orcid":false,"given":"Ariana L.","family":"Shaari","sequence":"additional","affiliation":[{"name":"The Thyroid, Head and Neck Cancer (THANC) Foundation  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Beute","sequence":"additional","affiliation":[{"name":"The Thyroid, Head and Neck Cancer (THANC) Foundation  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Mundi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ammar","family":"Matloob","sequence":"additional","affiliation":[{"name":"Department of Pathology Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azita S.","family":"Khorsandi","sequence":"additional","affiliation":[{"name":"Department of 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