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They are used to protect or displace vital structures, assist in positioning of the treatment beam for effective administration of radiotherapy, carry a radioactive material, shield healthy tissues of the oral cavity, and\/or maintain the desired mouth opening during radiotherapy. With close collaboration between radiation oncologist and oral health\u2009care provider, several IRS can be fabricated by the latter for appropriate targeting and delivery of planned radiation dose and optimized treatment results. Modification of these IRS based on individual patient need is recommended to maximize prosthesis utility. The purpose of this review is to discuss the various types of IRS and highlight their clinical utility and benefits in patients receiving radiation therapy in the head and neck cancers.<\/jats:p>","DOI":"10.1002\/hed.26848","type":"journal-article","created":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T13:21:46Z","timestamp":1630761706000},"page":"4010-4017","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Intraoral radiation stents\u2014Primer for clinical use in head and neck cancer therapy"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7066-4492","authenticated-orcid":false,"given":"Annu","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan 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