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We present two cases of OCC, one demonstrating invasion of the mandible and the other limited to the tongue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An 87\u2010year\u2010old male presented with a right\u2010sided buccogingival lesion. Biopsy results led to a diagnosis of verrucous hyperplasia, which was later revised to OCC. Additionally, a 94\u2010year\u2010old female presented with a left lateral tongue lesion. A biopsy showed in\u2010situ and invasive keratinizing squamous cell carcinoma that was later defined as a soft tissue OCC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Following surgical resection, the diagnosis of OCC was established in both patients. We provide a comprehensive literature review of OCC in the context of both case presentations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>OCC is a rare entity, which has a tendency to be misdiagnosed. We emphasize the importance of recognizing the common features of OCC in order to aid in accurate diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.26984","type":"journal-article","created":{"date-parts":[[2022,1,22]],"date-time":"2022-01-22T11:07:35Z","timestamp":1642849655000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cuneiform (cuniculatum) variant of oral squamous cell carcinoma revisited: Presentation of two cases and literature review of a rare entity"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3618-1013","authenticated-orcid":false,"given":"John E.","family":"Beute","sequence":"first","affiliation":[{"name":"The Thyroid, Head and Neck Cancer (THANC) Foundation  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5610-2642","authenticated-orcid":false,"given":"Gabriella T.","family":"Seo","sequence":"additional","affiliation":[{"name":"The Thyroid, Head and Neck Cancer (THANC) Foundation  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lily A.","family":"Greenberg","sequence":"additional","affiliation":[{"name":"The Thyroid, Head and Neck Cancer (THANC) Foundation  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Mundi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Icahn School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric M.","family":"Dowling","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Icahn School of Medicine at Mount Sinai  New York New York 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