{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:39:19Z","timestamp":1790642359189,"version":"4.1.0"},"reference-count":120,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Carotid body tumor (CBT) is a rare neoplasm that has been increasingly studied during the last decades; nevertheless, it continues to be a topic of controversy. This review aims to provide an update on the general features of CBT and particularly review different treatment strategies and primary outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data for this literature review were identified by PubMed, Scopus, and Medline. 93 articles from the initial search were included, as well as 28 relevant studies utilizing the snowballing method; totaling 121 articles about CBT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Main features such as anatomy, embryology, genetics, clinical presentation, and diagnosis of CBT are presented, followed by evidence of different treatment strategies such as radiotherapy, preoperative embolization, vascular resection, and vascular reconstruction. Main complications are also discussed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This review summarizes the most critical aspects regarding CBT. Future studies should compare different treatments to attain the best surgical results with lower morbidity rates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.27147","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T06:12:41Z","timestamp":1657865561000},"page":"2316-2332","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Current trends in carotid body tumors: Comprehensive review"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5101-1541","authenticated-orcid":false,"given":"Mauricio","family":"Gonzalez\u2010Urquijo","sequence":"first","affiliation":[{"name":"Tecnologico de Monterrey School of Medicine and Health Sciences  Monterrey Nuevo Le\u00f3n Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0733-0910","authenticated-orcid":false,"given":"Alejandra","family":"Castro\u2010Varela","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey School of Medicine and Health Sciences  Monterrey Nuevo Le\u00f3n Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8332-8682","authenticated-orcid":false,"given":"Alanna","family":"Barrios\u2010Ruiz","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey School of Medicine and Health Sciences  Monterrey Nuevo Le\u00f3n Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0233-0607","authenticated-orcid":false,"given":"David E.","family":"Hinojosa\u2010Gonzalez","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey School of Medicine and Health Sciences  Monterrey Nuevo Le\u00f3n Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6186-4345","authenticated-orcid":false,"given":"Ana Karen Garza","family":"Salas","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey School of Medicine and Health Sciences  Monterrey Nuevo Le\u00f3n Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0397-150X","authenticated-orcid":false,"given":"Erick Ambriz","family":"Morales","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey School of Medicine and Health Sciences  Monterrey Nuevo Le\u00f3n Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8442-514X","authenticated-orcid":false,"given":"Mirna","family":"Gonz\u00e1lez\u2010Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey School of Medicine and Health Sciences  Monterrey Nuevo Le\u00f3n Mexico"},{"name":"Tecnologico de Monterrey The Institute for Obesity Research  Monterrey Nuevo Le\u00f3n Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8548-6833","authenticated-orcid":false,"given":"Mario Alejandro","family":"Fabiani","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey School of Medicine and Health Sciences  Monterrey Nuevo Le\u00f3n Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2013.06.002"},{"issue":"6","key":"e_1_2_11_3_1","article-title":"Surgical complications of carotid body tumors surgery: a review","volume":"34","author":"Amato B","year":"2015","journal-title":"Int Angiol"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2018.10.019"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2008.01.015"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.2478\/s11536\u2010010\u20100015\u20108"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/1516\u20103180.2014.1323452"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/02688697.2019.1617404"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25805"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2018.04.032"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e3181eda61d"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.5604\/01.3001.0014.4872"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cphy.c100069"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.23829"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105\u2010017\u20100786\u20101"},{"key":"e_1_2_11_16_1","unstructured":"El\u2010NaggarAK ChanJKC GrandisJR TakataT SlootwegPJ;2017.WHO Classification of Head and Neck Tumours 4th Ed. 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