{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T15:03:25Z","timestamp":1789571005655,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T00:00:00Z","timestamp":1671062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2020J011124"],"award-info":[{"award-number":["2020J011124"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To develop a common follow\u2010up strategy for appropriate imaging examination at an appropriate time for nasopharyngeal carcinoma (NPC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Independent prognostic factors were identified by Cox regression analysis, and a nomogram model was developed. Random survival forest (RSF) model was constructed to depict probability of disease failure during a 5\u2010year follow\u2010up and establish a reasonable risk\u2010based follow\u2010up strategy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The nomogram model finally categorized the patients into three risk groups. RSF model demonstrated distribution trends for local and regional recurrences, bone metastasis, liver metastasis, and lung metastasis of NPC. Adequate imaging at follow\u2010up should be considered between 10 and 21\u2009months for patients at moderate\u2010risk of recurrence or metastasis and 7\u201336\u2009months for those at high\u2010risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The temporal distribution of incidence rates of recurrence or metastasis varied among different risk groups. We recommend implementing a focused and targeted imaging surveillance intervention at appropriate times to improve its efficiency and reduce costs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27277","type":"journal-article","created":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T08:06:17Z","timestamp":1671091577000},"page":"629-637","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Recommendation for imaging follow\u2010up strategy based on time\u2010specific disease failure for nasopharyngeal carcinoma"],"prefix":"10.1002","volume":"45","author":[{"given":"Ye","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University Fujian Cancer Hospital  Fuzhou People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiying","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of 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