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This makes it difficult to compare the effectiveness of different imaging and surgical techniques. To address this issue, this scoping review maps the literature on IPAs, focusing on four domains: clinical presentation, current localization methods, different surgical techniques, and histopathological features. A search of MEDLINE, Embase, and the Cochrane Library was conducted, with 19 studies meeting the inclusion criteria. The characteristics of IPAs on ultrasound, fine\u2010needle aspiration, CT, MRI, sestamibi\u2010based techniques, and selective venous sampling are summarized. Emerging imaging modalities, including autofluorescence, are introduced. Surgical methods and intraoperative factors that correlate with high success rates for removal are highlighted. This review also identifies gaps in knowledge to guide further research into this area.<\/jats:p>","DOI":"10.1002\/hed.27287","type":"journal-article","created":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T20:13:56Z","timestamp":1671826436000},"page":"706-720","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Intrathyroidal parathyroid adenomas: Scoping review on clinical presentation, preoperative localization, and surgical treatment"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0552-6314","authenticated-orcid":false,"given":"Shravan V.","family":"Gowrishankar","sequence":"first","affiliation":[{"name":"School of Clinical Medicine University of Cambridge  Cambridge 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