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The purpose of this study was to compare outcomes of TORS to open partial laryngectomy and transoral laser microsurgery (TLM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with clinical classification T1\u20102 supraglottic SCC diagnosed 2010\u20132019, treated with TORS, open partial laryngectomy, or TLM in the National Cancer Database were selected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One thousand six hundred three patients were included: 17% TORS, 26.5% TLM, 56.5% open. TORS patients had the lowest rates of adjuvant treatment (28.4% vs. TLM: 45.0%, open: 38.5%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and lower positive margin rates than TLM (16.9% vs. 30.5%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Thirty\u2010day and ninety\u2010day post\u2010operative mortality did not differ between the approaches. Five\u2010year survival was higher following TORS compared to open surgery (77.8% vs. 66.1%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.01); this difference persisted following matched\u2010pair analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>TORS may be a safe and effective surgical approach for early\u2010stage supraglottic SCC in appropriate patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27325","type":"journal-article","created":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T13:58:51Z","timestamp":1677247131000},"page":"972-982","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Role of transoral robotic surgery in surgical treatment of early\u2010stage supraglottic larynx carcinoma"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0630-4940","authenticated-orcid":false,"given":"Michael R.","family":"Papazian","sequence":"first","affiliation":[{"name":"NYU Grossman School of Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam S.","family":"Jacobson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Persky","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Persky","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,24]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"SEER Cancer Statistics Review, 1975\u20132018","author":"Howlader N","year":"2021"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000236095.97947.26"},{"key":"e_1_2_8_4_1","unstructured":"National Comprehensive Cancer Network.NCCN Clinical Practice Guidelines in Oncology: Head and Neck Cancers. 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