{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T04:52:49Z","timestamp":1768798369150,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T00:00:00Z","timestamp":1678665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To assess the efficacy of prophylactic versus reactive feeding strategy in oral cavity squamous cell carcinoma (OCSCC) patients receiving adjuvant radiation therapy (RT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a post hoc analysis of patients of OCSCC enrolled in a randomized trial comparing three adjuvant strategies. In this trial, till 2010, a prophylactic feeding approach was followed for all patients. Since January 2011, a reactive feeding approach was followed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and sixty\u2010eight in each cohort (total <jats:italic>n<\/jats:italic>\u00a0=\u2009526) were eligible for analysis after propensity score matching. At 6\u2009weeks post\u2010RT completion, the median weight loss in the prophylactic versus reactive cohort was 5 versus 3\u2009kg, <jats:italic>p<\/jats:italic>\u00a0=\u20090.002. At all other time points until 1 year, the median weight loss was lesser in reactive than in the prophylactic cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A reactive feeding tube approach should be preferred for OCSCC receiving adjuvant RT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27336","type":"journal-article","created":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T08:34:57Z","timestamp":1678696497000},"page":"1226-1236","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prophylactic versus reactive feeding approach in patients undergoing adjuvant radiation therapy for oral cavity squamous cell carcinoma: A propensity score matched\u2010pair analysis"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0744-4838","authenticated-orcid":false,"given":"Sarbani","family":"Ghosh Laskar","sequence":"first","affiliation":[{"name":"Department of 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