{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T03:50:23Z","timestamp":1784951423436,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to compare the outcomes of parent artery occlusion (PAO) versus stent\u2010assisted reconstruction in radiated nasopharyngeal carcinoma (NPC) patients with internal carotid artery (ICA) blowouts. A retrospective review from our institution (2011\u20132021) and systematic review of Pubmed and Embase (1995\u20132022) was performed. Twenty\u2010eight eligible studies were identified. Eighty\u2010six PAOs and 37 stent\u2010assisted reconstructions were analyzed, including 11 PAOs and 5 stents from our institution. Stents were associated with significantly higher incidence of overall re\u2010bleeding (16.2% [95% CI 7.4\u201331.9] vs. 4.6% [95% CI 1.3\u201313.5], <jats:italic>p<\/jats:italic>\u2009=\u20090.047), delayed stroke (5.4% [95% CI 1.3\u201319.4] vs. 0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.034) and reduced median survival (7.1 [95% CI 3.8\u201314.0] months vs. 29.0 [95% CI 9.4\u201363.4] months, <jats:italic>p<\/jats:italic>\u2009=\u20090.017) compared to PAO. There were no significant differences in terms of overall stroke, infection, extruded\/migrated foreign body, and peri\u2010procedure death. PAO is preferred over reconstructive treatment in patients with adequate collateral circulation.<\/jats:p>","DOI":"10.1002\/hed.27367","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T16:19:30Z","timestamp":1681143570000},"page":"1604-1614","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Deconstructive versus reconstructive approach to internal carotid artery blowout in radiated nasopharyngeal carcinoma: A tertiary center experience and systematic review"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7534-2545","authenticated-orcid":false,"given":"Xinni","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head &amp; Neck Surgery National University Hospital  Singapore 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