{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T03:59:04Z","timestamp":1778644744619,"version":"3.51.4"},"reference-count":44,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:00:00Z","timestamp":1683849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To explore how well a unique combination of hemoglobin\u2010to\u2010platelet ratio (HPR) and pretreatment maximum mouth opening (MMO) predicts the prevalence of radiation\u2010induced trismus (RIT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>HPR and MMO cutoff values (0.54 and 40.7\u2009mm) divided patients into two groups. To develop the novel HPR\u2010MMO index, four combinations of these factors were tested for predictive power: Group 1: HPR\u2009&gt;\u20090.54 and MMO\u2009&gt;\u200940.7\u2009mm; Group 2: HPR\u2009\u2264\u20090.54 but MMO\u2009&gt;\u200940.7\u2009mm; Group 3: HPR\u2009&gt;\u20090.54 but MMO\u2009\u2264\u200940.7\u2009mm; Group 4: HPR\u2009\u2264\u20090.54 and MMO\u2009\u2264\u200940.7\u2009mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data of 198 patients with LA\u2010NPC was analyzed retrospectively. RIT rates for Groups 1 to 4 were 10.2%, 15.2%, 25%, and 59.4%. Groups 2 and 3 were merged to generate HPR\u2010MMO index because of statistically equivalent RIT rates: Low\u2010risk: HPR\u2009&gt;\u20090.54 and MMO\u2009&gt;\u200940.7\u2009mm; Intermediate\u2010risk: HPR\u2009\u2264\u20090.54 but MMO\u2009&gt;\u200940.7\u2009mm or; HPR\u2009&gt;\u20090.54 but MMO\u2009\u2264\u200940.7\u2009mm; High\u2010risk: HPR\u2009\u2264\u20090.54 and MMO\u2009\u2264\u200940.7\u2009mm. It was revealed that the low\u2010, high\u2010, and intermediate\u2010risk group's RIT rates; 10.2%, 59.4%, and 19.2%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The novel HPR\u2010MMO index may to classify LA\u2010NPC patients into low, intermediate, and high\u2010risk RIT groups.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27400","type":"journal-article","created":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T04:10:08Z","timestamp":1683951008000},"page":"1823-1831","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The predictive usefulness of the novel \u201ccombined hemoglobin\u2010to\u2010platelet ratio and maximum mouth opening index\u201d on prevalence of radiation induced trismus in patients with nasopharyngeal 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