{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T11:08:00Z","timestamp":1749121680392,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T00:00:00Z","timestamp":1687478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Endoscopic\u2010assisted transoral surgery (TOS) for superficial cancer of the pharyngo\u2010esophageal junction (PEJ) is risk of stricture, and therapeutic outcomes are unclear. This study aimed to evaluate clinical outcomes of endoscopic\u2010assisted TOS for superficial PEJ cancers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively compared clinical outcomes of endoscopic\u2010assisted TOS for superficial PEJ cancers (group A) and of other sites in the hypopharynx (group B).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The group A comprised 12 lesions in 12 patients, and group B comprised 198 lesions in 146 patients. Group A and group B exhibited en bloc resection rates of 100% and 99%. Median operative times were 82 and 37\u2009min (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The frequency of stricture and local recurrence in group A was significantly higher in group B (42% vs. 1%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; 25% vs. 6%, <jats:italic>p<\/jats:italic>\u2009=\u20090.036). All adverse events could be managed with conservative treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Endoscopic\u2010assisted TOS is not ideal for treating superficial PEJ cancers compared to other sites.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27439","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T23:50:00Z","timestamp":1687650600000},"page":"2098-2107","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical outcome of <scp>endoscopic\u2010assisted<\/scp> transoral surgery for superficial cancer of pharyngo\u2010esophageal junction"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7662-6358","authenticated-orcid":false,"given":"Yasuaki","family":"Furue","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Endoscopy National Cancer Center Hospital East  Kashiwa Japan"},{"name":"Department of Gastroenterology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Hori","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Endoscopy National Cancer Center Hospital East  Kashiwa Japan"},{"name":"Department of Gastroenterology Ichinomiyanishi Hospital  Ichinomiya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0406-3976","authenticated-orcid":false,"given":"Toshifumi","family":"Tomioka","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery National Cancer Center Hospital East  Kashiwa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Fujii","sequence":"additional","affiliation":[{"name":"Division of Pathology, Exploratory Oncology Research and Clinical Trial Center National Cancer Center  Kashiwa Japan"},{"name":"Department of Molecular Pathology Yokohama City University Graduate School of Medicine  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3915-4229","authenticated-orcid":false,"given":"Wataru","family":"Okano","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery National Cancer Center Hospital East  Kashiwa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Shinozaki","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery National Cancer Center Hospital East  Kashiwa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0408-3494","authenticated-orcid":false,"given":"Tomohiro","family":"Kadota","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Endoscopy National Cancer Center Hospital East  Kashiwa 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