{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:09:49Z","timestamp":1747148989804,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T00:00:00Z","timestamp":1691539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Compare outcomes after surgery (S) or radiotherapy (RT) for T1a\u2010T1b glottic squamous cell carcinoma (T1GSCC) in a population\u2010based cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients diagnosed with T1GSCC from 1999 to 2020 were identified from a public database. Clinical, demographic, and social data were extracted. Treatment and patient groups and subgroups were compared with log\u2010rank test, Cox proportional test, and propensity\u2010score matched (PSM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eight hundred and eighty\u2010eight patients with T1GSCC were included in the study, with a median follow\u2010up of 61\u2009months. The 5\u2010 and 10\u2010year overall survival (OS) S versus RT were 76% versus 71% and 60% versus 52% (<jats:italic>p<\/jats:italic>\u2009=\u20090.02), respectively. In the subgroup analysis, S was associated with better OS for T1b, male, and public service patients (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). In the PSM cohort of S versus RT with 110 patients each, there was no significant difference in the OS, CSS, and LC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>T1GSCC has favorable outcomes with S or RT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27470","type":"journal-article","created":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T09:29:11Z","timestamp":1691573351000},"page":"2505-2514","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Real\u2010world evidence for oncological outcomes after radiotherapy or surgery for <scp>T1a\u2010T1b<\/scp> glottic squamous cell carcinoma: A population\u2010based cohort study"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4337-7575","authenticated-orcid":false,"given":"Gustavo Arruda","family":"Viani","sequence":"first","affiliation":[{"name":"Department of Medical Imagings, Hematology and Oncology, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo (FMRP\u2010USP)  Ribeir\u00e3o Preto Brazil"},{"name":"Latin America Cooperative Oncology Group (LACOG)  Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio Ynoe","family":"Moraes","sequence":"additional","affiliation":[{"name":"Latin America Cooperative Oncology Group (LACOG)  Porto Alegre Brazil"},{"name":"Division of Radiation Oncology, Department of Oncology, Kingston General Hospital Queen's University  Kingston Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo Nader","family":"Marta","sequence":"additional","affiliation":[{"name":"Latin America Cooperative Oncology Group (LACOG)  Porto Alegre Brazil"},{"name":"Department of Radiation Oncology Hospital Sirio Liban\u00eas  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Paulo","family":"Kowalski","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Otorhinolaryngology AC Camargo Cancer Center (ACCCC)  Sao Paulo Brazil"},{"name":"Department of Head and Neck Surgery, S\u00e3o Paulo State Cancer Institute (ICESP), School of Medicine University of S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7055-3557","authenticated-orcid":false,"given":"Andre Guimaraes","family":"Gouveia","sequence":"additional","affiliation":[{"name":"Latin America Cooperative Oncology Group (LACOG)  Porto Alegre Brazil"},{"name":"Department of Radiation Oncology Americas Centro de Oncologia Integrado  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2014.06.032"},{"key":"e_1_2_10_3_1","first-page":"3","article-title":"Comparative evaluation of the effectiveness of radiotherapy, surgery and combined treatment of stage I\u2010II laryngeal cancer (T1\u20102NoMo) based on the data of a cooperative randomized study","volume":"3","author":"Ogol'tsova ES","year":"1990","journal-title":"Vestn Otorinolaringol"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010009\u20101028\u20102"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2018.09.012"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.75.7385"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489420905616"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2021.103298"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002027.pub2"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103\u2010016\u20102103\u20108"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23504"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010018\u201030218\u2010x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2022.01.010"},{"key":"e_1_2_10_14_1","unstructured":"Funda\u00e7\u00e3o Oncocentro de S\u00e3o Paulo (FOSP) Registro Hospitalar de C\u00e2ncer (RHC).Base de dados do RHC.https:\/\/200.144.1.68\/cgi-bin\/dh?rhc\/rhc-geral.def. 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