{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:45:47Z","timestamp":1790739947762,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T00:00:00Z","timestamp":1692576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We report the results of an international multi\u2010institutional cohort of oligometastatic (OMD) head and neck cancer (HNC) patients treated with SBRT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with OMD HNC (\u22645 metastases) treated with SBRT between 2008 and 2016 at six institutions were included. Treated metastasis control (TMC), progression\u2010free survival (PFS), and overall survival (OS) were analyzed by multivariable analysis (MVA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010two patients with 84 HNC oligometastases were analyzed. The TMC rate at 1 and 2\u2009years were 80% and 66%, with a median time to recurrence of 10.1\u2009months. The median PFS and OS were 4.7 and 23.3\u2009months. MVA identified a PTV point maximum (BED)10\u2009&gt;\u2009100\u2009Gy as a predictor of improved TMC (HR\u2009=\u20090.31, <jats:italic>p<\/jats:italic>\u2009=\u20090.034), and a cumulative PTV\u2009&gt;\u200948\u2009cc as having worse PFS (HR\u2009=\u20092.99, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Favorable TMC and OS was observed in OMD HNCs treated with SBRT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27488","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T02:11:24Z","timestamp":1692670284000},"page":"2627-2637","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Outcomes for oligometastatic head and neck cancer treated with stereotactic body radiotherapy: Results from an international multi\u2010institutional consortium"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9821-1505","authenticated-orcid":false,"given":"Badr","family":"Id Said","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Odette Cancer Centre Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Mutsaers","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Odette Cancer Centre Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanbo","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Odette Cancer Centre Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zain A.","family":"Husain","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Odette Cancer Centre Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tithi","family":"Biswas","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University Hospitals Seidman Cancer Center  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8747-2710","authenticated-orcid":false,"given":"Roi","family":"Dagan","sequence":"additional","affiliation":[{"name":"University of Florida Health Proton Therapy Institute  Jacksonville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darby","family":"Erler","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Odette Cancer Centre Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Foote","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Princess Alexandra Hospital University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander V.","family":"Louie","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Odette Cancer Centre Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin","family":"Redmond","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology and Molecular Radiation Sciences Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Ricardi","sequence":"additional","affiliation":[{"name":"Department of Oncology University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjun","family":"Sahgal","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Odette Cancer Centre Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8508-9280","authenticated-orcid":false,"given":"Ian","family":"Poon","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Odette Cancer Centre Sunnybrook Health Science Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2018.06.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802656"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2009.04.014"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.0395"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.04.003"},{"issue":"6","key":"e_1_2_7_7_1","first-page":"378","article-title":"Oligometastases revisited. 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