{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T22:09:40Z","timestamp":1766182180003,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T00:00:00Z","timestamp":1695168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The clinical use of Integra\u2122 has expanded to include scalp reconstruction since its FDA approval in 1996. Integra\u2122, or dermal regeneration template, can be utilized in patients who are elderly with multiple medical comorbidities. Well\u2010established Integra\u2122 techniques utilize skin grafting 1\u20132\u2009weeks following evidence of template vascularity. Most studies show the time to graft placement as &lt;30\u2009days, with almost all &lt;52\u2009days. No single article proposes a time frame for applying STSG after neodermis regeneration. Therefore, we aimed to describe our protocol to define a time frame for delaying scalp reconstruction with STSG following dermal regeneration. Over the last several years, the senior author has utilized a delayed reconstruction with skin grafting method where\u2010in Integra\u2122 is applied to either debrided bone or exposed pericranium in selected patients, and allowed to mature for ~6\u2009weeks before performing skin grafting. The results have been predictable, reproducible, and have yielded high levels of patient and provider satisfaction due to the improved contour cosmesis. In this pictorial essay, the authors' novel protocol is detailed.<\/jats:p>","DOI":"10.1002\/hed.27520","type":"journal-article","created":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T13:15:10Z","timestamp":1695215710000},"page":"2967-2974","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Delayed skin grafting protocol following Integra\u2122 application for non\u2010radiated scalp reconstruction for decreased wound depth and improved contour"],"prefix":"10.1002","volume":"45","author":[{"given":"Mac Kenzie","family":"Reece","sequence":"first","affiliation":[{"name":"Department of General Surgery Wright State University, Boonshoft School of Medicine  Dayton Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of General Surgery Wright State University, Boonshoft School of Medicine  Dayton Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Benintendi","sequence":"additional","affiliation":[{"name":"Wright State University, Boonshoft School of Medicine  Dayton Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey","family":"Ward","sequence":"additional","affiliation":[{"name":"Miami Valley Hospital  Dayton Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Thatcher","sequence":"additional","affiliation":[{"name":"Miami Valley Hospital  Dayton Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Michael","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Wright State University, Boonshoft School of Medicine  Dayton Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8920-9481","authenticated-orcid":false,"given":"Sameep P.","family":"Kadakia","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Wright State University, Boonshoft School of Medicine  Dayton Ohio USA"},{"name":"Department of Surgery Wright State University, Boonshoft School of Medicine  Dayton Ohio USA"},{"name":"Premier Head and Neck Oncology and Reconstructive Surgery Wright State University, Boonshoft School of Medicine  Dayton Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100039\u20101693401"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/scs.0000000000005717"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/prs.0000000000007884"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2021.07.009"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jormas.2020.06.016"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.08.022"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/gox.0000000000001074"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.7181\/acfs.2020.00269"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/698385"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12576"},{"key":"e_1_2_7_12_1","unstructured":"ThorntonJ.Skin grafts and skin substitutes.https:\/\/plasticsurgery.stanford.edu\/content\/dam\/sm\/plasticsurgery\/documents\/education\/microsurgery\/FlapsSelectedReadings.pdf"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010198110000\u201000005"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0305\u20104179(95)93866\u2010i"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/scs.0b013e3181d8418e"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582\u20104934.2005.tb00491.x"},{"issue":"3","key":"e_1_2_7_17_1","first-page":"305","article-title":"Partial dermal regeneration is induced by biodegradable collagen\u2010glycosaminoglycan grafts","volume":"62","author":"Murphy GF","year":"1990","journal-title":"Lab Invest"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000222609.40461.68"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004030050460"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S50046"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2009.0403"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/prs.0000000000006072"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.27520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T11:40:23Z","timestamp":1697888423000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.27520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,20]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1002\/hed.27520"],"URL":"https:\/\/doi.org\/10.1002\/hed.27520","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"type":"print","value":"1043-3074"},{"type":"electronic","value":"1097-0347"}],"subject":[],"published":{"date-parts":[[2023,9,20]]},"assertion":[{"value":"2023-06-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}