{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T06:12:03Z","timestamp":1771654323163,"version":"3.50.1"},"reference-count":6,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T00:00:00Z","timestamp":1697068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head & Neck"],"published-print":{"date-parts":[[2024,1]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>McCune\u2010Albright syndrome is a rare disorder characterized by polyostotic fibrous dysplasia (FD), caf\u00e9\u2010au\u2010lait skin pigmentation, and endocrine dysfunction. Extensive FD in the craniofacial region can present significant challenges in terms of disease control and carries a high risk of permanent visual impairment.<\/jats:p><\/jats:sec>Methods<\/jats:title>We present a case of medically and surgically resistant FD that required nine optic nerve decompressions.<\/jats:p><\/jats:sec>Results<\/jats:title>The condition was ultimately controlled with the use of the denosumab agent.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The case highlights the importance and potential efficacy of denosumab in resistant FD management, particularly in cases involving sensitive organs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27546","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T10:24:46Z","timestamp":1697106286000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["RANK\u2010L<\/scp> inhibitor as a promising agent for refractory extensive craniofacial fibrous dysplasia: A case report"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6970-1874","authenticated-orcid":false,"given":"Moataz D.","family":"Abouammo","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Tanta University Tanta Egypt"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6722-2244","authenticated-orcid":false,"given":"Mohammad Bilal","family":"Alsavaf","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA"},{"name":"Department of Neurological Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"Prevedello","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA"},{"name":"Department of Neurological Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luma","family":"Ghalib","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes, and Metabolism The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison M.","family":"Boyce","sequence":"additional","affiliation":[{"name":"Metabolic Bone Disorders Unit National Institute of Dental and Craniofacial Research, National Institutes of Health Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo L.","family":"Carrau","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA"},{"name":"Department of Neurological Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200508000-00028"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM193704292161701"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-7-S1-S2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2214862"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014\u20101371"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3649"}],"container-title":["Head & Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.27546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T05:49:40Z","timestamp":1717652980000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.27546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,12]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/hed.27546"],"URL":"https:\/\/doi.org\/10.1002\/hed.27546","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,12]]},"assertion":[{"value":"2023-07-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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