{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:01:07Z","timestamp":1791662467113,"version":"4.3.4"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sinonasal NUT carcinoma is an extremely rare, lethal malignancy with limited literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A case series was conduction of all patients with sinonasal NUT carcinoma at a single institution between 2010 and 2022. Survival and associated were evaluated. A systematic review of the literature was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 12 patients, followed for a median of 1.5\u2009years, the median overall survival (OS) and disease\u2010specific survival (DSS) were both 14.6\u2009months. Patients with maxillary sinus tumors were 91% more likely to survive (hazard ratio [HR]: 0.094, 95% confidence interval [CI]: 0.011\u20130.78, <jats:italic>p<\/jats:italic>\u2009=\u20090.011). Patients with higher\u2010stage disease stage had worse OS (stage IVb\u2010c vs. III\u2010IVa, <jats:italic>p<\/jats:italic>\u2009=\u20090.05). All three patients who were alive with no evidence of disease received induction chemotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For patients with sinonasal NUT carcinoma, the median survival was 15\u2009months but better with lower\u2010stage and maxillary tumors. Induction chemotherapy may be beneficial.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27553","type":"journal-article","created":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T06:46:35Z","timestamp":1697697995000},"page":"29-36","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Sinonasal <scp>NUT<\/scp> carcinoma: A consecutive case series and systematic review"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1231-3301","authenticated-orcid":false,"given":"Uma","family":"Ramesh","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas M. D. Anderson Cancer Center  Houston Texas USA"},{"name":"School of Medicine Baylor College of Medicine  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2570-1706","authenticated-orcid":false,"given":"Kevin J.","family":"Contrera","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas M. D. Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasim","family":"Shakibai","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas M. D. Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3903-8204","authenticated-orcid":false,"given":"Shirley Y.","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas M. D. Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bledi","family":"Brahimaj","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The University of Texas M. D. Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianna","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas M. D. Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle D.","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Pathology The University of Texas M. D. 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Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaan","family":"Raza","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The University of Texas M. D. Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"DeMonte","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The University of Texas M. D. Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehab Y.","family":"Hanna","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery The University of Texas M. D. 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