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Hypoglossal nerve function was evaluated with genioglossus needle EMG, functional measures with the Iowa oral performance instrument (IOPI), and multi\u2010frequency tissue composition with tongue EIM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Tongue EIM conductivity was higher for patients with EMG\u2010confirmed cranial nerve XII neuropathy than those without (<jats:italic>p<\/jats:italic>\u2009=\u20090.005) and in patients with mild versus normal EMG reinnervation ratings (16\u2009kHz EIM: <jats:italic>p<\/jats:italic>\u2009=\u20090.051). Tongue EIM correlated with IOPI strength measurements (e.g., anterior maximum isometric lingual strength: <jats:italic>r<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.62, <jats:italic>p<\/jats:italic>\u2009=\u20090.020).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Tongue EIM measures related to tongue strength and the presence of XII neuropathy. Noninvasive tongue EIM may be a convenient adjunctive biomarker to assess tongue health in OPC survivors.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27618","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T14:09:50Z","timestamp":1703254190000},"page":"581-591","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Tongue electrical impedance myography correlates with functional, neurophysiologic, and clinical outcome measures in long\u2010term oropharyngeal cancer survivors with and without hypoglossal neuropathy: An exploratory study"],"prefix":"10.1002","volume":"46","author":[{"given":"Nathan J.","family":"Hansen","sequence":"first","affiliation":[{"name":"Department of Electrical and Computer Engineering The University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5972-0278","authenticated-orcid":false,"given":"Karin","family":"Woodman","sequence":"additional","affiliation":[{"name":"Department of Neurology The University of Texas, MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Buoy","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Division of Surgery The University of Texas, MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5122-7497","authenticated-orcid":false,"given":"Shitong","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Division of Surgery The University of Texas, MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carly E. 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