{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:51:20Z","timestamp":1792043480777,"version":"4.4.0"},"reference-count":48,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T00:00:00Z","timestamp":1707350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007531","name":"Southern Taiwan Science Park","doi-asserted-by":"publisher","award":["BX\u201003\u201004\u201004\u2010 110"],"award-info":[{"award-number":["BX\u201003\u201004\u201004\u2010 110"]}],"id":[{"id":"10.13039\/501100007531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011913","name":"Kaohsiung Veterans General Hospital","doi-asserted-by":"publisher","award":["KSVGH110\u2010099"],"award-info":[{"award-number":["KSVGH110\u2010099"]}],"id":[{"id":"10.13039\/501100011913","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Segmental bone defects of the mandible result in the complete loss of the affected region. We had incorporated the pressure\u2010reducing device (PRD) designs into the customized mandible prostheses (CMP) and conducted a clinical trial to evaluate this approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seven patients were enrolled in this study. We examined the association among the history of radiotherapy, the number of CMP regions, the number of chin regions involved, and CMP exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included five men and two women with an average age of 55\u2009years. We excised tumors with an average weight of 147.8\u2009g and the average weight of the CMP was 68.5\u2009g. No significant difference between the two weights was noted (<jats:italic>p<\/jats:italic>\u2009=\u20090.3882). Three patients received temporary dentures and the CMP remained stable in all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of PRD in CMP may address the previous challenges associated with CMP, but further research is necessary.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27660","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T10:05:04Z","timestamp":1707386704000},"page":"1614-1624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The use of customized <scp>3D\u2010printed<\/scp> mandibular prostheses with <scp>pressure\u2010reducing<\/scp> device: A clinical trial"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9222-1550","authenticated-orcid":false,"given":"Chun\u2010Feng","family":"Chen","sequence":"first","affiliation":[{"name":"School of Dentistry College of Dental Medicine, Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Department of Oral and Maxillofacial Surgery Kaohsiung Veterans General Hospital  Kaohsiung Taiwan"},{"name":"Dental Laboratory Technology Shu Zen College of Medicine &amp; Management  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Ming","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Dentistry College of Dental Medicine, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010Chin","family":"Huang","sequence":"additional","affiliation":[{"name":"Laser and Additive Manufacturing Technology Center Industrial Technology Research Institute  Hsinchu Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2010Ho","family":"Liu","sequence":"additional","affiliation":[{"name":"Laser and Additive Manufacturing Technology Center Industrial Technology Research Institute  Hsinchu Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling\u2010Lin","family":"Wang","sequence":"additional","affiliation":[{"name":"KSVGH Originals &amp; Enterprises Kaohsiung Veterans General Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010Feng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science and Environmental Biology College of Life Science, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping\u2010Ho","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Dentistry College of Dental Medicine, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40902-015-0031-3"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2017.01.006"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000004119"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-015-1193-2"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.12.026"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.7181\/acfs.2018.01830"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000005228"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcs.1854"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2017.12.003"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2013.10.011"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.07.013"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2020.103758"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-005-0984-7"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.H.01038"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0021-8782.2002.00108.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/9880454"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2008.03.002"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.05.023"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/joms.2002.29817"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.06.011"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jds.2023.09.011"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2016.06.170"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-22292-z"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.12.038"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.1.4.667"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/apm.12099"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/0954411914556137"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms140918488"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2010.00665.x"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2011.09.012"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1586\/erd.12.70"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.4224"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0171086"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b16159"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22558"},{"issue":"6","key":"e_1_2_9_37_1","first-page":"513","article-title":"The nature of host tissue destruction in tumor invasion. 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