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Secondary outcomes include\u00a0complications and postoperative feeding requirements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifteen studies met the inclusion criteria with a total of 442 patients. Two\u2010year DFS is\u00a0reported from 30.0 to 50.0% and 5\u2010year DFS ranges from 15.0 to 57.1%. Five\u2010year DSS ranges from 28.0 to 57.1%. Two\u2010year OS ranges from 38.8 to 52.0% and 5\u2010year OS ranges from 15.5 to 57.1%. Complications include pharyngocutaneous fistula (0.0\u201371.4%), carotid artery rupture (2.9\u201313.3%), and stomal stenosis (4.2\u201320.0%). Complete oral feeding achieved following surgery ranges from 61.9 to 100.0%, while complete gastrostomy tube dependence ranges from 0.0 to 28.6%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Salvage surgery for residual or recurrent hypopharyngeal squamous cell carcinoma has a relatively high complication rate and should be offered to patients with the understanding of a guarded prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27794","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T10:54:15Z","timestamp":1715165655000},"page":"2725-2736","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Salvage surgery for recurrent or residual hypopharyngeal squamous cell carcinoma: A systematic review"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3779-2027","authenticated-orcid":false,"given":"Peter 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