{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T13:35:30Z","timestamp":1771076130207,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T00:00:00Z","timestamp":1718409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To investigate feasibility of utilizing enhanced neuromuscular blocking agents with selective recovery protocol during thyroid surgery with intraoperative neuromonitoring (IONM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two\u2010hundred and ninety patients were randomized into two groups: group A 0.3\u2009mg\/kg rocuronium and group B 0.6\u2009mg\/kg. Sugammadex 2\u2009mg\/kg was injected if needed followed initial vagal stimulation (V0). Electromyography signals from vagus and recurrent laryngeal nerves before and after resection were recorded as V1, V2, R1, and R2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In group B, 30 patients (20.7%) had V0 signals &lt;100\u2009\u03bcV, compared to 9 (6.2%) in group A. After sugammadex administration, 144 patients (99.3%) in both groups achieved positive V1 signals. Group B demonstrated a shorter surgical time from rocuronium injection to V2 stimulation compared to group A, accompanied by a significantly lower incidence of intraoperative body movement (0 vs. 16 patients).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>0.6\u2009mg\/kg rocuronium with selective use 2\u2009mg\/kg sugammadex for IONM in thyroid surgery can meet both anesthesia and surgery demands.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27826","type":"journal-article","created":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T07:53:11Z","timestamp":1718437991000},"page":"2917-2925","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Feasibility of the enhanced neuromuscular blockade recovery protocol with selective use of sugammadex in thyroid surgery with intraoperative neuromonitoring"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6712-2879","authenticated-orcid":false,"given":"Shuwen","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Head &amp; Neck Surgery Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Shanghai Medical College, Fudan University  Shanghai China"},{"name":"Cancer Research Institute Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhirong","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changming","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cancer Prevention Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjun","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Surgery Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Shanghai Medical College, Fudan University  Shanghai China"},{"name":"Cancer Research Institute Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Surgery Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Shanghai Medical College, Fudan University  Shanghai China"},{"name":"Cancer Research Institute Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongliang","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Surgery Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Shanghai Medical College, Fudan University  Shanghai China"},{"name":"Cancer Research Institute Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Surgery Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Shanghai Medical College, Fudan University  Shanghai China"},{"name":"Cancer Research Institute Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weibo","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Surgery Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Shanghai Medical College, Fudan University  Shanghai China"},{"name":"Cancer Research Institute Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinhai","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Surgery Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Shanghai Medical College, Fudan University  Shanghai China"},{"name":"Cancer Research Institute Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4144-8560","authenticated-orcid":false,"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Surgery Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Shanghai Medical College, Fudan University  Shanghai China"},{"name":"Cancer Research Institute Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,15]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2008.05870.x"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aei314"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200702000-00016"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25577"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-017-4004-9"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-009-0316-8"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2017.01.086"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7226-6"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-005-0355-8"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2005.08.027"},{"key":"e_1_2_12_12_1","first-page":"25","article-title":"The technique of intraoperative neuromonitoring in thyroid surgery","volume":"19","author":"Dionigi G","year":"2010","journal-title":"Surg Technol Int"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000132260.34503.02"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-005-0351-z"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2010.11.006"},{"issue":"15","key":"e_1_2_12_16_1","article-title":"Clinical guidelines on intraoperative neuromonitoring during thyroid and parathyroid surgery","volume":"3","author":"Sun H","year":"2015","journal-title":"Ann Transl Med"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X0203000109"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0b013e32833d56b7"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen037"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000248224.42707.48"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/08941939.2020.1805055"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2013.12.022"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000004379"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2019.97.6.282"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.27826","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T10:07:28Z","timestamp":1731665248000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.27826"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,15]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/hed.27826"],"URL":"https:\/\/doi.org\/10.1002\/hed.27826","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,15]]},"assertion":[{"value":"2023-09-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}