{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:39:27Z","timestamp":1787319567376,"version":"build-2736575974"},"reference-count":48,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Thyroidectomy can lead to significant challenges such as neck pain, disability, and limited range of motion. Therefore, our objective is to conduct a systematic review and meta\u2010analysis of clinical trials to investigate the clinical effectiveness of neck stretching exercises in alleviating neck pain and self\u2010reported disability immediately after thyroidectomy. We systematically searched PubMed, CENTRAL, Scopus, and Web of Science from inception until July 28th, 2023. We assessed the selected trials for the risk of bias using both the RoB\u20102 and ROBINS\u2010I tools. Our specific outcomes were the severity of neck pain and self\u2010reported disability after thyroidectomy. The results were synthesized using risk ratio (RR) and standardized mean differences (SMD) with 95% confidence intervals (CI) in a random\u2010effects model using Stata software. Nine clinical trials, comprising five randomized and four non\u2010randomized trials, were included, with a total of 1026 patients. Neck stretching exercises were significantly associated with improved mean pain scores both after 1\u2009week (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009625 patients, SMD\u2009=\u2009\u22122.43, 95% CI [\u22124.65, \u22120.22],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.03,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u200998%) and 1\u2009month (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009545 patients, SMD\u2009=\u2009\u22124.11, 95% CI [\u22128.12, \u22120.11],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.04,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u200999%). Similarly, neck stretching exercises were significantly associated with improved mean self\u2010reported disability scores both after 1\u2009week (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009298 patients, SMD\u2009=\u2009\u22120.70, 95% CI [\u22121.36, \u22120.04],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.04,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u200987%) and 1\u2009month (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009298 patients, SMD\u2009=\u2009\u22120.42, 95% CI [\u22120.65, \u22120.19],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0004,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090%). The pooled analysis showed heterogeneity (chi\u2010square\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009&gt;\u200980%), except for the mean self\u2010reported neck disability score after 1\u2009month, which showed homogeneity (chi\u2010square\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&gt;\u20090.01,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090%). This systematic review and meta\u2010analysis, involving 1026 patients, revealed the potential benefits of neck stretching exercises in alleviating neck pain and self\u2010reported disability after thyroidectomy. However, further research is required to address methodological limitations, evaluate long\u2010term outcomes, investigate potential moderators (i.e., the duration or intensity of the exercise program), and explore patients' analgesic consumption.\n                  <\/jats:p>","DOI":"10.1002\/hed.27906","type":"journal-article","created":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T05:38:19Z","timestamp":1722922699000},"page":"2632-2649","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The effectiveness of neck stretching exercises in alleviating neck pain and self\u2010reported disability after thyroidectomy: A systematic review and meta\u2010analysis of clinical trials"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1244-7769","authenticated-orcid":false,"given":"Ebraheem","family":"Albazee","sequence":"first","affiliation":[{"name":"Kuwait Institute for Medical Specializations (KIMS)  Kuwait City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3127-9644","authenticated-orcid":false,"given":"Hemail M.","family":"Alsubaie","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery St. James's Hospital  Dublin Ireland"},{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery and Communication Sciences King Faisal Specialist Hospital and Research Centre  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7837-4032","authenticated-orcid":false,"given":"Justin M.","family":"Hintze","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isobel","family":"O'Riordan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conrad","family":"Timon","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery St. James's Hospital  Dublin Ireland"},{"name":"Trinity College Dublin The University of Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kinsella","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery St. James's Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Lennon","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery St. James's Hospital  Dublin Ireland"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Royal Victoria Eye and Ear Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conall W. 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