{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:28:58Z","timestamp":1784305738580,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T00:00:00Z","timestamp":1728000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004376","name":"Terry Fox Research Institute","doi-asserted-by":"publisher","award":["1126"],"award-info":[{"award-number":["1126"]}],"id":[{"id":"10.13039\/501100004376","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000245","name":"Michael Smith Health Research BC","doi-asserted-by":"publisher","award":["17632"],"award-info":[{"award-number":["17632"]}],"id":[{"id":"10.13039\/501100000245","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["163974"],"award-info":[{"award-number":["163974"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008002","name":"Vancouver Coastal Health Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study assesses the feasibility of real\u2010time surgical navigation to plan and guide sequential steps during mandible reconstruction on a series of cadaveric specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An image\u2010guided surgical (IGS) system was designed including customized mandible and fibula fixation devices with navigation reference frames and an accompanied image\u2010guided software. The mandibular and fibular segmental osteotomies were performed using the IGS in all five cadaveric patients. Procedural time and cephalometric measurements were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five real\u2010time IGS mandibulectomy and fibular reconstruction were successfully performed. The mean Dice score and Hausdorff\u201095 distance between the planned and actual mandible reconstructions was 0.8\u2009\u00b1\u20090.08 and 7.29\u2009\u00b1\u20094.81\u2009mm, respectively. Intercoronoid width, interangle width, and mandible projection differences were 1.15\u2009\u00b1\u20091.17\u2009mm, 0.9\u2009\u00b1\u20090.56\u2009mm, and 1.47\u2009\u00b1\u20091.62\u2009mm, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study presents the first demonstration of a comprehensive image\u2010guided workflow for mandibulectomy and fibular flap reconstruction on cadaveric specimens and resulted in adequate cephalometric accuracy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27954","type":"journal-article","created":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T05:07:07Z","timestamp":1728104827000},"page":"640-650","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Intraoperative Real\u2010Time Image\u2010Guided Fibular Harvest and Mandibular Reconstruction: A Feasibility Study on Cadaveric Specimens"],"prefix":"10.1002","volume":"47","author":[{"given":"Georgia","family":"Grzybowski","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, Faculty of Applied Science University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly Murray","family":"Stewart","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Faculty of Applied Science University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6688-502X","authenticated-orcid":false,"given":"Thomas D.","family":"Milner","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Department of Surgery, Faculty of Medicine University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat Bahat","family":"Dinur","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Department of Surgery, Faculty of Medicine University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orla M.","family":"McGee","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Faculty of Applied Science University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Pakdel","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Department of Surgery, Faculty of Medicine University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khanh Linh","family":"Tran","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Department of Surgery, Faculty of Medicine University of British Columbia  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