{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T12:02:10Z","timestamp":1772539330816,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG3M1103"],"award-info":[{"award-number":["CMRPG3M1103"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study evaluates the impact of maxillary sinus mucosa preservation on radiographic outcomes after an inferior maxillectomy and soft\u2010tissue free flap reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 90 patients in two cohorts (mucosal sacrifice versus mucosa preservation) were evaluated from an institutional dataset. Imaging was reviewed at set time points and sinus scores were allotted based on a modification of the Lund\u2014MacKay system. Patients were evaluated for changes in sinus scores. A univariate (UVA) and multivariate (MVA) analysis was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In gp1 (mucosal sacrifice), mean postoperative sinus score was 1.21\u2009\u00b1\u20091.30 (<jats:italic>p<\/jats:italic>\u2009=\u2009&lt;\u20090.001) at 24\u2009months. On UVA, advanced T\u2010stage at 12\u2009months (OR 7.143, 95% CI 1.484\u201334.384, <jats:italic>p<\/jats:italic>\u2009=\u20090.014) and 24\u2009months (OR 5.500, 95% CI 1.219\u201324.813, <jats:italic>p<\/jats:italic>\u2009=\u20090.027), and on MVA, advanced T\u2010stage were associated with increased odds for higher sinus score (OR 4.993, 95% CI 1.084\u201322.995, <jats:italic>p<\/jats:italic>\u2009=\u20090.039). In Gp2 (Mucosa preserved), the mean postoperative sinus score was 0.31\u2009\u00b1\u20090.47 (<jats:italic>p<\/jats:italic>\u2009=\u20090.021) at 24\u2009months. On UVA and MVA, no predictors were identified for a higher sinus score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Following an inferior maxillectomy and soft\u2010tissue free flap reconstruction, notably reduced sinus scores were seen in patients with preservation of the remaining maxillary sinus mucosa.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.27992","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T11:18:34Z","timestamp":1731323914000},"page":"956-961","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Maxillary Sinus Mucosa Preservation Versus Mucosal Sacrifice: Radiographic Outcomes After Inferior Maxillectomy and Soft\u2010Tissue Free Flap Reconstruction"],"prefix":"10.1002","volume":"47","author":[{"given":"Ya\u2010Hsuan","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Linkou Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6583-7096","authenticated-orcid":false,"given":"Rushil Rajiv","family":"Dang","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery Chang Gung Memorial Hospital  Linkou Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan\u2010Shiun","family":"Fan","sequence":"additional","affiliation":[{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min\u2010Chi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Public Health and Biostatistics Consulting Center Chang Gung University  Taoyuan Taiwan"},{"name":"Division of Movement Disorders, Department of Neurology Chang Gung Memorial Hospital  Linkou Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Feng","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Linkou Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung\u2010Kang","family":"Tsao","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery Chang Gung Memorial Hospital  Linkou Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4776-2262","authenticated-orcid":false,"given":"Po\u2010Wen","family":"Chuang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Linkou Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen Michelle","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Linkou Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi\u2010Kuang","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Linkou Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Keelung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3677-4249","authenticated-orcid":false,"given":"Chun\u2010Ta","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Linkou Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung\u2010Jan","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Linkou Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3582-9938","authenticated-orcid":false,"given":"Shiang\u2010Fu","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery Chang Gung Memorial Hospital  Linkou Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences, College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2009.00672.x"},{"key":"e_1_2_10_4_1","volume-title":"SEER Cancer Statistics Review 1975\u20102018","author":"Howlader N.","year":"2021"},{"issue":"1","key":"e_1_2_10_5_1","first-page":"7","article-title":"An Overview of Detection and Screening of Oral Cancer in Taiwan","volume":"18","author":"Kao S. Y.","year":"2015","journal-title":"Chinese Journal of Dental Research"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17020665"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29718"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27575"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23849"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e3180325b6c"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.17959"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.27992","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T12:29:51Z","timestamp":1739363391000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.27992"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,11]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1002\/hed.27992"],"URL":"https:\/\/doi.org\/10.1002\/hed.27992","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,11]]},"assertion":[{"value":"2024-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}