{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T04:08:04Z","timestamp":1745986084742,"version":"3.40.4"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T00:00:00Z","timestamp":1736035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The superior thyroid artery (STA) as a recipient vessel in free flap reconstruction may theoretically impact thyroid function. This study aimed to assess whether the use of the STA has an adverse effect on thyroid function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of 101 head and neck reconstructive cases. Thyroid function tests were reviewed within 1\u2009year of surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The STA was used in 40 cases. The STA cohort had significantly higher TSH levels than the non\u2010STA cohort (7.34 v. 2.87\u2009mU\/L, <jats:italic>p<\/jats:italic>\u2009=\u20090.02). About 27.5% developed subclinical post\u2010operative hypothyroidism and 17.5% required new levothyroxine supplementation in the STA group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This represents the first study to our knowledge assessing the impact of the STA as a recipient vessel on postoperative thyroid function. While we found a statistically significant difference in average TSH after using the STA, the average TSH\/FT4 values were subclinical. Post\u2010operative monitoring for hypothyroidism is warranted in this population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.28049","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T06:21:47Z","timestamp":1736144507000},"page":"1455-1461","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of the Superior Thyroid Artery as a Recipient Artery in Head and Neck Free Flap Reconstruction: Effects on Post\u2010Operative Hypothyroidism"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7771-1802","authenticated-orcid":false,"given":"Kaitlynne Y.","family":"Pak","sequence":"first","affiliation":[{"name":"Division of Otolaryngology\u2010Head and Neck Surgery, Department of Surgery Cedars Sinai Medical Center  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Nunez","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2010Head and Neck Surgery, Department of Surgery Cedars Sinai Medical Center  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harsh","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery UCLA Medical Center  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5423-509X","authenticated-orcid":false,"given":"Allen S.","family":"Ho","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2010Head and Neck Surgery, Department of Surgery Cedars Sinai Medical Center  Los Angeles California USA"},{"name":"Samuel Oschin Comprehensive Cancer Institute Cedars\u2010Sinai Medical Center  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2558-4682","authenticated-orcid":false,"given":"Jon","family":"Mallen\u2010St. Clair","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2010Head and Neck Surgery, Department of Surgery Cedars Sinai Medical Center  Los Angeles California USA"},{"name":"Samuel Oschin Comprehensive Cancer Institute Cedars\u2010Sinai Medical Center  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.22212"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2011.03.002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1272\/jnms.66.176"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2013-0237"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0000000000000242"},{"key":"e_1_2_7_8_1","first-page":"236","article-title":"The Effect of Substitution Therapy on Symptoms in Patients With Hypothyroidism Following Treatment for Laryngeal and Hypopharyngeal Carcinomas","volume":"33","author":"Lo Galbo A. 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