{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:26:52Z","timestamp":1761179212721,"version":"build-2065373602"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T00:00:00Z","timestamp":1739145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lipoblastoma\u2010like tumors (LLTs) are uncommon lipogenic neoplasms that predominantly occur in the vulva of female individuals. This study presents a novel case of LLT located on the tongue with an IDH1 mutation. Both the site of occurrence and molecular alterations are reported for the first time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 65\u2010year\u2010old female patient presented to the hospital 1\u2009month ago with an incidental finding of a multinodular mass at the right lingual margin. We performed an incision along the outer edge of the mass and completely excised it 0.5\u2009cm beyond its periphery. The final pathological diagnosis after routine examination confirmed a lipoblastoma\u2010like tumor. Furthermore, Next\u2010generation sequencing revealed the presence of mutations in IDH1.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study presents the first documented case of LLT, thereby expanding its anatomical site of tongue and confirming the presence of a significant IDH1 mutation, thus enhancing our understanding of the molecular alterations in LLT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.28104","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T00:17:49Z","timestamp":1739233069000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lipoblastoma\u2010Like Tumor of the Tongue With\n                    <scp>IDH1<\/scp>\n                    Mutation: A Case Report and Literature Review"],"prefix":"10.1002","volume":"47","author":[{"given":"Dongpo","family":"Li","sequence":"first","affiliation":[{"name":"Department of Stomatology The Affiliated Hospital of Qingdao University  Qingdao China"},{"name":"School of Stomatology Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangqi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pathology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pathology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailei","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Pathology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1644-1818","authenticated-orcid":false,"given":"Shuangyi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Stomatology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohong","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Pathology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102559.2002.01409.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000448"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379\u2010018\u20100102\u2010y"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.modpat.2023.100246"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.modpat.2023.100252"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428\u2010020\u201002883\u20109"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14020"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpr.2022.300678"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.17884"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2015.05.013"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555\u20100904"},{"key":"e_1_2_9_13_1","first-page":"223","article-title":"Benign 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