{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T21:51:12Z","timestamp":1785189072352,"version":"3.55.0"},"reference-count":12,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Intra\u2010arterial chemotherapy (IAC) can be highly effective for advanced head and neck cancers but often necessitates complex procedures and prolonged hospitalization. Herein, we demonstrate the utility of the repeatable microcatheter access port (ReMAP) system for streamlining IAC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two patients with advanced head and neck cancers underwent repeated IAC via a subcutaneously implanted ReMAP. Procedural feasibility, safety, and clinical outcomes were assessed and compared to conventional techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Case 1 involved a 42\u2010year\u2010old male with advanced maxillary sinus carcinoma who received eight IAC sessions of high\u2010dose cisplatin without complications. Follow\u2010up imaging confirmed complete tumor resolution. Case 2 was a 52\u2010year\u2010old female with primary intraosseous squamous cell carcinoma of the jaw who completed eight IAC sessions via an external carotid arterial sheath, then four sessions with the ReMAP, reducing inpatient requirements, and achieving tumor control.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The ReMAP system enabled safe and effective IAC administration while reducing patient burden.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.28205","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T06:14:19Z","timestamp":1748585659000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Superficial Temporal Artery\u2010Based\n                    <scp>ReMAP<\/scp>\n                    : A Case Report Series in Head and Neck Cancer Intra\u2010Arterial Chemotherapy"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2537-627X","authenticated-orcid":false,"given":"Wataru","family":"Makino","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Central Japan International Medical Center  Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobukazu","family":"Fuwa","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Central Japan International Medical Center  Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Central Japan International Medical Center  Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Central Japan International Medical Center  Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihito","family":"Matsui","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Central Japan International Medical Center  Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miwako","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Ise Red Cross Hospital  Ise Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Toyomasu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mie University Hospital  Tsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinori","family":"Takada","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mie University Hospital  Tsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880140505"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2023.11.031"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24930"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100347(200010)22:7<687::aid\u2010hed8>3.0.co;2\u2010w"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270\u2010017\u20101635\u2010z"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14225529"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11604\u2010021\u201001202\u20109"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11604\u2010014\u20100361\u20106"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270\u2010018\u20102111\u20100"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.58530"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyv151"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432\u2010015\u20102069\u20100"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.28205","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hed.28205","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.28205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:01:10Z","timestamp":1772985670000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.28205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,30]]},"references-count":12,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/hed.28205"],"URL":"https:\/\/doi.org\/10.1002\/hed.28205","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,30]]},"assertion":[{"value":"2025-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}