{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:59:52Z","timestamp":1772996392187,"version":"3.50.1"},"reference-count":46,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The long\u2010term outcomes and social reintegration following open partial horizontal laryngectomy (OPHL) type II\/III after radiation failure remain unclear. This study aimed to evaluate the outcomes of salvage OPHL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 56 recurrent cases after radiotherapy and 84 unirradiated cases who underwent OPHL type II\/III at Kitasato University Hospital between November 1997 and October 2023. Overall survival (OS), disease\u2010free survival (DFS), larynx preservation (LP), laryngo\u2010esophageal dysfunction\u2010free survival (LEDFS), and return to work (RTW) were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 10\u2009years, OS, DFS, LP, and LEDFS were 76%, 73%, 93%, and 67% in recurrent cases and 65%, 58%, 94%, and 58% in unirradiated cases, with no significant difference. RTW rates were 87% and 81%, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.57).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>OPHL type II\/III after radiation failure demonstrated favorable long\u2010term outcomes and RTW rates, supporting its role as a valuable salvage option.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.28253","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T09:14:14Z","timestamp":1752830054000},"page":"3331-3339","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Outcomes and Social Reintegration After Salvage Open Partial Horizontal Laryngectomy Type\n                    <scp>II<\/scp>\n                    \/\n                    <scp>III<\/scp>\n                    for Radiation Failure"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9297-4456","authenticated-orcid":false,"given":"Shunsuke","family":"Miyamoto","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Kano","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohei","family":"Tsutsumi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Kitasato University School of Medicine  Sagamihara 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