{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T01:10:02Z","timestamp":1699319402471},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,18]],"date-time":"2006-07-18T00:00:00Z","timestamp":1153180800000},"content-version":"vor","delay-in-days":10182,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head Neck"],"published-print":{"date-parts":[[1978,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In dealing with a child with a structural defect, an overall diagnosis must be formulated. Such a diagnosis makes it possible to provide genetic counseling for the parents and an accurate prediction relative to such a child's future development. Because there are a great many abnormalities involving the head and neck, it is hoped that the approach set forth in this article will allow for a systematic narrowing of the diagnostic possibilities. Nomenclature is established. Prenatal\u2010onset defects are described, including both single primary defects (malformations and deformations) and multiple malformation syndromes (chromosomal abnormalities, genetic disorders, defects resulting from teratogenic factors, and disorders of unknown etiology). Genetic and environmental factors of postnatal developmental problems are also discussed.<\/jats:p>","DOI":"10.1002\/hed.2890010106","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T19:42:11Z","timestamp":1172000531000},"page":"35-46","source":"Crossref","is-referenced-by-count":2,"title":["Dysmorphology: An approach to diagnosing children with structural defects of the head and neck"],"prefix":"10.1002","volume":"1","author":[{"given":"Kenneth Lyons","family":"Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilyn C.","family":"Higginbottom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(73)80078-2"},{"key":"e_1_2_1_3_2","volume-title":"Birth Defects Atlas and Compendium","author":"Bergsma DB","year":"1973"},{"key":"e_1_2_1_4_2","first-page":"513","article-title":"Classification and nomenclature of morphological defects","volume":"1","author":"Christiansen RL","year":"1975","journal-title":"Lancet"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bmb.a071327"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420140302"},{"key":"e_1_2_1_7_2","volume-title":"Syndromes of the Head and Neck","author":"Gorlin RJ","year":"1975"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(75)80063-1"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(76)80414-3"},{"key":"e_1_2_1_10_2","first-page":"226","volume-title":"Williams' Obstetrics","author":"Hellman LM","year":"1971"},{"key":"e_1_2_1_11_2","volume-title":"Mental Retardation: An Atlas of Diseases with Associated Physical Abnormalities","author":"Holmes LB","year":"1972"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)91291-9"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(74)80559-7"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(75)80709-8"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1962.10663250"},{"key":"e_1_2_1_16_2","volume-title":"Mendelian Inheritance in Man. 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