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This study is based on a retrospective review of 884 clinical records of previously untreated HC or LEC. Seventy percent of patients revealed palpable nodes at their first examination, with a higher percentage for HC (73%) than LEC (62%). The 5\u2010year survival rate was divided by three in the presence of contralateral, bilateral, or fixed nodes, or in cases of nodes exceeding 3 cm. Multiple positive nodes, extracapsular spread, or lower\u2010neck positive nodes significantly decreased survival, doubled the number of neck recurrences, and tripled the number of distant metastases while control at the primary site remained unvaried.<\/jats:p>","DOI":"10.1002\/hed.2890100104","type":"journal-article","created":{"date-parts":[[2007,2,20]],"date-time":"2007-02-20T21:27:56Z","timestamp":1172006876000},"page":"14-18","source":"Crossref","is-referenced-by-count":53,"title":["Lymph node invasion in hypopharynx and lateral epilarynx carcinoma: A prognostic factor"],"prefix":"10.1002","volume":"10","author":[{"given":"J. L.","family":"Lefebvre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Castelain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C. La","family":"De Torre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Delobelle\u2010Deroide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Vankemmel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(76)90315-9"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19801101)46:9<1974::AID-CNCR2820460913>3.0.CO;2-A"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198204000-00001"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1982.tb01581.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1981.00790480001001"},{"key":"e_1_2_1_7_2","first-page":"73","article-title":"Les ad\u00e9nopathies cervicales des cancers du sinus piriforme: \u00e9tude clinique et r\u00e9sultats de la radioth\u00e9rapie","volume":"29","author":"Brugere J","year":"1980","journal-title":"J Fr Otorhinolaryngol"},{"key":"e_1_2_1_8_2","first-page":"345","article-title":"Etude comparative de la signification des ad\u00e9nopathies dans les cancers de l'hypopharynx, du larynx et de la margelle. A propos de 574 dossiers","volume":"99","author":"Trotoux J","year":"1982","journal-title":"Ann Otolaryngol"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1983.93.5.556"},{"key":"e_1_2_1_10_2","first-page":"275","article-title":"Les ad\u00e9nopathies des \u00e9patheliomas du sinus piriforme. A propos de 100 cas","volume":"105","author":"David JM","year":"1984","journal-title":"Rev Laryngol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(85)80033-5"}],"container-title":["Head &amp; Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.2890100104","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.2890100104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T22:11:03Z","timestamp":1697926263000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.2890100104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,9]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,9]]}},"alternative-id":["10.1002\/hed.2890100104"],"URL":"https:\/\/doi.org\/10.1002\/hed.2890100104","archive":["Portico"],"relation":{},"ISSN":["0148-6403","1930-2398"],"issn-type":[{"value":"0148-6403","type":"print"},{"value":"1930-2398","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,9]]}}}