{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T15:46:47Z","timestamp":1782748007002,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K09308"],"award-info":[{"award-number":["23K09308"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to investigate the survival impact and predictive factors of cervical lymph node metastasis (CLNM) in patients with maxillary gingival squamous cell carcinoma (MGSCC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study included 81 patients with MGSCC who underwent radical surgery from 2008 to 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Pathological CLNM was observed in 24 patients, prevalently in levels IB and II on the ipsilateral side. Cox proportional hazards model analysis revealed histologic grade, CLNM, and local recurrence as independent prognostic factors for 5\u2010year disease\u2010specific survival. Multivariate analysis identified tumoral spread to the gingivobuccal sulcus and the maxillary tuberosity as independent risk factors for CLNM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CLNM is associated with poor survival in patients with MGSCC. Primary tumors extending into the gingivobuccal sulcus or maxillary tuberosity may predict CLNM, particularly at levels IB and II. These findings may provide valuable insights for optimizing neck management strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70021","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T07:36:01Z","timestamp":1756539361000},"page":"219-226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Survival Impact and Risk Factors of Cervical Lymph Node Metastasis in Maxillary Gingival Squamous Cell Carcinoma: A Retrospective Study of 81 Patients"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0861-9599","authenticated-orcid":false,"given":"Takeshi","family":"Kuroshima","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgical Oncology Graduate School of Medical and Dental Sciences, Institute of Science Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7141-5279","authenticated-orcid":false,"given":"Naoya","family":"Kinoshita","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgical Oncology Graduate School of Medical and Dental Sciences, Institute of Science Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5789-2693","authenticated-orcid":false,"given":"Naoto","family":"Nishii","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgical Oncology Graduate School of Medical and Dental Sciences, Institute of Science Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3406-3686","authenticated-orcid":false,"given":"Yu","family":"Oikawa","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgical Oncology Graduate School of Medical and Dental Sciences, Institute of Science Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5905-8176","authenticated-orcid":false,"given":"Takuma","family":"Kugimoto","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgical Oncology Graduate School of Medical and Dental Sciences, Institute of Science Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4573-9971","authenticated-orcid":false,"given":"Hideaki","family":"Hirai","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Faculty of Dentistry &amp; 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