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Subjects were graded through clinical tongue functional measures and gold\u2010standard needle EMG. We collected HDS\u2013EMG in three tongue tasks: relaxation, protrusion, and isometric maximum effort. The HDS\u2013EMG was decomposed into motor unit spike train estimates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Muscle relaxation HDS\u2013EMG contained spikes consistent with fasciculation potential morphology. During tongue protrusion, a case of confirmed CN XII neuropathy exhibited an elevated motor unit (MU) discharge rate and fewer MUs (45.71\u2009peaks\/s, 3 estimated MUs) compared to the control (11.63\u2009peaks\/s, 11 estimated MUs). During isometric contraction, the case exhibited an average discharge rate of 3.96\u2009peaks\/s on 3\u2009MU estimates, whereas the control had a discharge rate of 2.58\u2009peaks\/s on 5 MU estimates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Non\u2010invasive tongue HDS\u2013EMG appears to show potential sensitivity for detecting reduced MU recruitment in hypoglossal neuropathy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70025","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:36:37Z","timestamp":1756460197000},"page":"195-205","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tongue Surface Electromyography Detects Reduced Motor Unit Recruitment in Oropharyngeal Cancer Survivors With Hypoglossal Neuropathy"],"prefix":"10.1002","volume":"48","author":[{"given":"Nathan J.","family":"Hansen","sequence":"first","affiliation":[{"name":"Department of Electrical and Computer Engineering The University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"Hutcheson","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Division of Surgery The University of Texas, MD Anderson Cancer Center  Houston Texas USA"},{"name":"Division of Radiation Oncology The University of Texas, MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly","family":"McMillan","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Division of Surgery The University of Texas, MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5122-7497","authenticated-orcid":false,"given":"Shitong","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Division of Surgery The University of Texas, MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8197-5886","authenticated-orcid":false,"given":"Katelyn","family":"Vidad","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Division of Surgery The University of Texas, MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8971-6870","authenticated-orcid":false,"given":"Carly E.","family":"Barbon","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Division of Surgery The University of Texas, MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Woodman","sequence":"additional","affiliation":[{"name":"Department of Neurology Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolaas C.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Neurology Baylor College of Medicine  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering The University of Illinois Chicago  Chicago Illinois USA"},{"name":"Richard and Loan Hill Department of Biomedical Engineering The University of Illinois Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the OPC\u2010SURVIVOR Program Working 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