{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T21:14:35Z","timestamp":1769634875340,"version":"3.49.0"},"reference-count":69,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T00:00:00Z","timestamp":1757116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T00:00:00Z","timestamp":1757116800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["WA 5500\/1\u20101"],"award-info":[{"award-number":["WA 5500\/1\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Accurate preoperative differentiation of parotid gland tumors (PGTs) is essential for facial nerve preservation. This study evaluates a novel, real\u2010time multiparametric ultrasound (mpUS) approach combining B\u2010mode, shear wave elastography (SWE), and contrast\u2010enhanced ultrasound (CEUS), based on qualitative image interpretation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eighty\u2010nine patients with 91 PGTs underwent mpUS prior to surgery or ultrasound\u2010guided biopsy. Two blinded experts independently reviewed the images and reached consensus through real\u2010time discussion. Only qualitative features were assessed. Histopathology served as the reference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>mpUS achieved 83% sensitivity (95% CI: 62.6\u201394.0), 94% specificity (95% CI: 84.3\u201398.1), and 91% accuracy (95% CI: 82.4\u201396.3). CEUS and SWE provided complementary perfusion and stiffness data. CCDS was excluded due to limited value.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>mpUS improves diagnostic accuracy compared to single\u2010modality US and supports early, targeted treatment. Limitations include the small number of malignancies, single\u2010center design, and qualitative evaluation. Broader use may require training and equipment access.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70036","type":"journal-article","created":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T09:37:22Z","timestamp":1757151442000},"page":"392-406","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multiparametric Ultrasound for Preoperative Assessment of Parotid Tumors: A Novel Diagnostic Pathway"],"prefix":"10.1002","volume":"48","author":[{"given":"Katharina Margherita","family":"Wakonig","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t Zu Berlin, and Berlin Institute of Health  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus 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