{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T01:49:30Z","timestamp":1777081770490,"version":"3.51.4"},"reference-count":46,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Buccinator myomucosal flaps (BMFs) have been proposed as a reconstructive solution for defects of the tongue and oral floor; however, their harvest requires preservation of the facial artery and vein. This study aimed to evaluate the oncologic safety of this approach compared with free fasciocutaneous flaps (FFF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective multicenter case\u2013control study including cT1\u2013T3 cN0 tongue\/oral floor squamous cell carcinoma was performed. Cases received BMFs while controls received FFFs. The primary endpoint was progression\u2010free survival (PFS) tested for non\u2010inferiority. Secondary endpoints were overall survival (OS), disease\u2010specific survival (DSS), and cumulative incidence of local, regional, and distant recurrence using competing\u2010risk methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 615 patients (BMF\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009390; FFF\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009225) with comparable baselines were included. Five\u2010year PFS was 69.8% (BMF) versus 66.2% (FFF); adjusted HR (FFF vs. BMF) 0.87 (95% CI: 0.43\u20131.78), meeting non\u2010inferiority. Five\u2010year OS was 77.9% versus 73.5%. Cumulative incidence of recurrence was similar: local 7.5% versus 8.3%, regional 6.3% versus 6.1%, and distant 2.1% versus 1.7%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Preservation of the facial artery and vein during selective neck dissection did not compromise oncologic outcomes. Facial\u2010vessel\u2013based BMFs are a valid option for small\u2010to\u2010medium tongue\/oral floor defects in appropriately selected cN0 patients when meticulous level I clearance is performed and a pull\u2010through resection is not required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70082","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T11:18:58Z","timestamp":1761218338000},"page":"827-836","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Oncologic Safety of Facial\u2010Vessel\u2013Based Buccinator Myomucosal Flaps for Tongue and Oral Floor Reconstruction: A Retrospective Multicenter Case\u2013Control Study"],"prefix":"10.1002","volume":"48","author":[{"given":"Luigi Angelo","family":"Vaira","sequence":"first","affiliation":[{"name":"Maxillofacial Surgery Operative Unit, Department of Medicine, Surgery and Pharmacy University of Sassari  Sassari 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M.","family":"Chiesa\u2010Estomba","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Biodonostia Research Institute, Osakidetza Donostia University Hospital  San Sebastian Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio Navarro","family":"Cu\u00e9llar","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Department Hospital Gregorio Mara\u00f1on, Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Consorti","sequence":"additional","affiliation":[{"name":"Division of Maxillofacial Surgery, Department of Neurological Sciences Marche University Hospitals\u2014Umberto I  Ancona Italy"},{"name":"Department of Biomedical Sciences and Public Health Polytechnic University of Marche  Ancona 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