{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:05:17Z","timestamp":1791234317829,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T00:00:00Z","timestamp":1765670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T00:00:00Z","timestamp":1765670400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["T32GM144273"],"award-info":[{"award-number":["T32GM144273"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Parathyroidectomy is typically curative for primary hyperparathyroidism (PHPT) and may lead to health\u2010related quality of life (HRQL) improvements. We aim to evaluate general and disease\u2010specific HRQL changes in patients undergoing surgery for PHPT from their perspective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients completed three patient\u2010reported outcome measure (PROM) surveys before and after surgery: (1) Worry survey; (2) Voice Handicap Index\u201010 (VHI\u201010); and (3) Patient\u2010Reported Outcome Measurement Information System Global\u201010 (PROMIS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty\u2010four patients were included with a median age of 65\u2009years, with 39 females (89%) included. Thirty\u2010two patients (73%) had a single adenoma, and 12 (27%) had multigland disease (parathyroid hyperplasia). Worry scores related to parathyroid cancer, parathyroid surgery, and parathyroid\u2010related problems significantly improved post\u2010operatively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). On PROMIS assessment, there were improved scores in the physical health domain, mental health domain, and general health following parathyroid surgery for PHPT (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with PHPT demonstrated significant improvements in HRQL following surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70129","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T06:38:02Z","timestamp":1765780682000},"page":"1303-1310","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Health\u2010Related Quality of Life in Patients Undergoing Surgery for Primary Hyperparathyroidism: Patient Reported Outcome Measures"],"prefix":"10.1002","volume":"48","author":[{"given":"Lily N.","family":"Trinh","sequence":"first","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery Massachusetts Eye and Ear, Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Tulane University  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Okenwa C.","family":"Okose","sequence":"additional","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery Massachusetts Eye and Ear, Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Otolaryngology\u2010Head &amp; Neck Surgery University of Tennessee Health Science Center  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5611-5833","authenticated-orcid":false,"given":"Amr H.","family":"Abdelhamid\u2010Ahmed","sequence":"additional","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery Massachusetts Eye and Ear, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2462-6775","authenticated-orcid":false,"given":"Yoshiyuki","family":"Saito","sequence":"additional","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery Massachusetts Eye and Ear, Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Surgery Keio University School of Medicine  Tokyo 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Otolaryngology\u2010Head and Neck Surgery Massachusetts Eye and Ear, Harvard Medical School  Boston Massachusetts USA"},{"name":"Division of Otolaryngology\u2010Head and Neck Surgery, Department of Surgery NorthShore University HealthSystem  Evanston Illinois USA"},{"name":"The University of Chicago, Pritzker School of Medicine  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7329-8560","authenticated-orcid":false,"given":"Anthony Y.","family":"Cheung","sequence":"additional","affiliation":[{"name":"Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology\u2010Head and Neck Surgery Massachusetts Eye and Ear, Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Anesthesia &amp; Critical Care University of Chicago  Chicago Illinois 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