{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T10:00:28Z","timestamp":1780999228325,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The association between elective nodal irradiation (ENI) and oncological outcomes in clinically node\u2010negative (cN0) sinonasal squamous cell carcinoma (SCC) and olfactory neuroblastoma (ONB) treated with postoperative chemoradiotherapy remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed cN0 sinonasal SCC and ONB patients receiving postoperative chemoradiotherapy at a single institution. Propensity score matching was performed to minimize confounding. Survival outcomes were assessed using Kaplan\u2013Meier estimates, and logistic regression identified factors associated with specific failure patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 62 eligible patients (36 SCC, 26 ONB; median follow\u2010up 44\u2009months), ENI was associated with a lower nodal recurrence rate (4.8% vs. 34.1%; OR 0.10,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.030) but not with overall or recurrence\u2010free survival (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Perineural invasion was independently associated with worse recurrence\u2010free survival. The association between ENI and reduced nodal recurrence appeared more pronounced in ONB.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite the small sample size, ENI was associated with reduced nodal recurrence but not with improved survival in cN0 sinonasal SCC and ONB.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70152","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T10:10:33Z","timestamp":1767089433000},"page":"1437-1446","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Elective Nodal Irradiation and Oncologic Outcomes in Node\u2010Negative Olfactory Neuroblastoma and Sinonasal Squamous Cell Carcinoma: A Propensity\u2010Score Matched Analysis"],"prefix":"10.1002","volume":"48","author":[{"given":"Shuo\u2010Fu","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Heavy Particles &amp; Radiation Oncology Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Wen","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Heavy Particles &amp; Radiation Oncology Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"School of Medicine, College of Medicine, National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien\u2010Fu","family":"Yeh","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Medicine, National Yang Ming Chiao Tung University  Taipei Taiwan"},{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Wai","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Ying","family":"Lan","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Medicine, National Yang Ming Chiao Tung University  Taipei Taiwan"},{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun\u2010Ting","family":"Chao","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Medicine, National Yang Ming Chiao Tung University  Taipei Taiwan"},{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying\u2010Ju","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Ying","family":"Shiau","sequence":"additional","affiliation":[{"name":"Department of Heavy Particles &amp; Radiation Oncology Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pin\u2010I","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Heavy Particles &amp; Radiation Oncology Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"School of Medicine, College of Medicine, National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,30]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21820"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2013.09.014"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21752"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.03.036"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.793351"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3857\/roj.2022.00514"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13194802"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13112835"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2024.05.029"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27361"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.104618"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.10.067"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(03)00080-4"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2012.03.024"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(02)03940-8"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.3857\/roj.2018.00416"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27512"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-66179-7"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2401"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1692479"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2022.106123"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034518756297"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29732"},{"key":"e_1_2_12_25_1","article-title":"Failure Patterns of Recurrence in Patients With Localized Esthesioneuroblastoma Following Surgery and Adjuvant Radiotherapy Without Elective Nodal Irradiation","volume":"15","author":"Katano A.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13014-016-0595-9"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2024.106698"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2018.04.041"}],"container-title":["Head &amp; 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