{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T13:06:43Z","timestamp":1775567203693,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Subglottic stenosis (SGS) is a narrowing of the airway below the glottis and may be congenital or acquired. While prolonged intubation is the most common cause of acquired SGS, other etiologies remain incompletely understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 37\u2010year\u2010old woman presented with a four\u2010year history of mild progressive stridor, dysphonia, and chronic cough. Her medical history was notable for Graves' disease, treated initially with long\u2010term carbimazole followed by radioactive iodine (RAI). She had never been intubated and had no autoimmune or rheumatologic disease. Awake fiberoptic endoscopy raised suspicion of SGS, which was confirmed by preoperative magnetic resonance imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Suspension microlaryngoscopy with biopsy and dilation revealed a Myer\u2010Cotton grade II SGS with an irregular aspect and exposed cartilage. Histopathology demonstrated chronic inflammation, fibrosis, and reactive epithelial changes consistent with radiation\u2010induced injury. After a second endoscopic dilation, only a minor anterior synechia remained, without evidence of recurrent stenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case report highlights a temporal association between RAI therapy and the subsequent development of SGS, supported by histopathological findings suggestive of radiation\u2010induced tissue injury. In the absence of other established risk factors, RAI treatment may represent a rare but clinically relevant cause of acquired SGS, a complication not previously reported in the literature.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70157","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T11:39:28Z","timestamp":1767181168000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Subglottic Stenosis After Radioactive Iodine Treatment for Graves' Disease: A Case Report"],"prefix":"10.1002","volume":"48","author":[{"given":"Claire","family":"Ettlin","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Inselspital, University Hospital and University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Giger","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Inselspital, University Hospital and University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Jaquet","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Inselspital, University Hospital and University of Bern  Bern Switzerland"},{"name":"Service d'ORL et chirurgie cervico\u2010faciale, D\u00e9partement de chirurgie R\u00e9seau hospitalier neuch\u00e2telois  Neuch\u00e2tel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5666-2092","authenticated-orcid":false,"given":"Samuel","family":"Tschopp","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Inselspital, University Hospital and University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.11.43"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0030\u20106665(05)70210\u20103"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003\u20104975(93)90406\u20108"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/joma\u201025\u20104"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.1255"},{"key":"e_1_2_9_7_1","first-page":"273","article-title":"Radiation\u2010Associated Airway Necrosis","volume":"13","author":"Alraiyes A. H.","year":"2013","journal-title":"Ochsner Journal"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1258\/002221503768200048"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.legalmed.2016.03.004"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2025.104643"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2019.00075"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.70157","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hed.70157","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.70157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T12:31:30Z","timestamp":1775565090000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.70157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,31]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/hed.70157"],"URL":"https:\/\/doi.org\/10.1002\/hed.70157","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,31]]},"assertion":[{"value":"2025-10-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}