{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T10:01:01Z","timestamp":1780999261135,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Obstructive sleep apnea (OSA) may contribute to fatigue in head and neck cancer patients undergoing chemotherapy and radiotherapy, particularly as both have the potential to impact the mechanics and dynamics of the airway. We conducted a scoping review and exploratory meta\u2010analysis to evaluate the risk of OSA following chemoradiation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, Web of Science, EMBASE, and Cochrane Library were searched for studies assessing incident OSA after radiotherapy or chemotherapy. Eligible studies isolated the effect of one treatment and reported OSA rates in each group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 559 papers identified, 110 were duplicates and 30 underwent full\u2010text review; 13 met criteria for exploratory meta\u2010analysis. A modest, nonsignificant trend toward increased risk of mild OSA was observed with radiotherapy (\n                      <jats:italic>z<\/jats:italic>\n                      \u2009=\u20091.42,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.15). Chemotherapy was not associated with mild (\n                      <jats:italic>z<\/jats:italic>\n                      \u2009=\u2009\u22120.83,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.41) or moderate (\n                      <jats:italic>z<\/jats:italic>\n                      \u2009=\u20090.00,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.00) OSA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Studies are limited in size and number, and do not support increased risk of OSA with radiotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70163","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T12:04:37Z","timestamp":1768824277000},"page":"1587-1594","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Obstructive Sleep Apnea Following Head and Neck Chemoradiation: A Scoping Review With Exploratory Meta\u2010Analysis"],"prefix":"10.1002","volume":"48","author":[{"given":"Augustin G. L.","family":"Vannier","sequence":"first","affiliation":[{"name":"Pritzker School of Medicine University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil S.","family":"Kondamuri","sequence":"additional","affiliation":[{"name":"Department of Surgery, Section of Otolaryngology\u2014Head and Neck Surgery University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan S.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Surgery, Section of Otolaryngology\u2014Head and Neck Surgery University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janya","family":"Allen","sequence":"additional","affiliation":[{"name":"University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nihar","family":"Rama","sequence":"additional","affiliation":[{"name":"Pritzker School of Medicine University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3664-1208","authenticated-orcid":false,"given":"Rachel","family":"Nordgren","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishant","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Surgery, Section of Otolaryngology\u2014Head and Neck Surgery University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7242-4943","authenticated-orcid":false,"given":"Phillip S.","family":"LoSavio","sequence":"additional","affiliation":[{"name":"Department of Surgery, Section of Otolaryngology\u2014Head and Neck Surgery University of Chicago  Chicago Illinois 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