{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:58:45Z","timestamp":1792688325993,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The risk of postoperative hemorrhage (POH) with use of nonsteroidal anti\u2010inflammatory drugs (NSAIDs) after trans\u2010oral robotic surgery (TORS) oropharyngectomy is poorly described in the existing literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective propensity\u2010matched cohort study was performed using the TriNetX database, with cohort assignments based on perioperative NSAID administration within 7\u2009days of surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>1761 patients undergoing TORS oropharyngectomy were identified, and divided into two equal propensity\u2010matched cohorts of 621. 660 patients (37.5%) received postoperative NSAIDs. The overall hemorrhage rate was 5.5%. There was no significant difference in primary POH (&lt;\u20091.5% in the NSAID group and 1.2% in the group without NSAIDs), secondary POH (5.2% vs. 4.2%, OR\u2009=\u20091.243, 95% CI\u2009=\u20090.732, 2.112), emergency room (ER) presentation within 30\u2009days (11.0% vs. 10.6%, OR\u2009=\u20091.034, 95% CI\u2009=\u20090.722, 1.480), or 30\u2010day mortality (&lt;\u20091.5% and &lt;\u20090.9%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this study, NSAID use after TORS was not associated with an increased risk of primary or secondary POH, 30\u2010day return to ER, or 30\u2010day mortality rates. Only 37.5% of patients in this study received postoperative NSAIDS. NSAIDs may be underutilized in the treatment of post\u2010TORS pain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70211","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T15:04:57Z","timestamp":1772982297000},"page":"1858-1864","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Assessing the Risk of Postoperative Hemorrhage With\n                    <scp>NSAID<\/scp>\n                    Use After Transoral Robotic Surgery"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6259-9491","authenticated-orcid":false,"given":"John A.","family":"Dewey","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery West Virginia University School of Medicine  Morgantown West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1952-0626","authenticated-orcid":false,"given":"Ryan S.","family":"Ziltzer","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery West Virginia University School of Medicine  Morgantown West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8621-6168","authenticated-orcid":false,"given":"Meghan T.","family":"Turner","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery West Virginia University School of Medicine  Morgantown West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2005.10.004"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000227184.90514.1a"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000199899.00479.75"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.808465"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28580"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24677"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11701\u2010015\u20100542\u2010z"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813486254"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813503446"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11701\u2010021\u201001190\u2010y"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2013.5097"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2022.106248"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33995"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/17512433.2021.1863787"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29876"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820947013"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599821996297"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/oto2.17"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.990"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2018.1461238"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215121004734"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2020.102649"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11701\u2010022\u201001448\u2010z"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01752"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2021.105301"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.26020"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.32251"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2017.04.014"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.70211","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hed.70211","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.70211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:21:11Z","timestamp":1780496471000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.70211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,24]]},"references-count":28,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/hed.70211"],"URL":"https:\/\/doi.org\/10.1002\/hed.70211","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,24]]},"assertion":[{"value":"2025-07-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}