{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:23:16Z","timestamp":1783164196585,"version":"3.54.6"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mandibular reconstruction suffers from limitations in automation and objectivity. This study aimed to develop an automated framework to address these challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A novel approach combining statistical shape modeling and 3D deep learning was developed. Trained on 200 CT scans and validated in 80 clinical cases, its performance was compared to expert manual planning by evaluating reconstruction accuracy, bone contact area, and planning time. Finally, design experiments were performed in five clinical cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The automated method demonstrated high accuracy (DSC: 0.874) and real\u2010time efficiency. It significantly outperformed manual planning in bone contact area (106.2 vs. 94.6\u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      ) and reduced planning time by 85%. Postoperative results showed excellent implant alignment (2.1\u2009mm deviation) and high patient satisfaction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The proposed automated framework successfully enhances the efficiency and quality of mandibular reconstruction, meeting clinical needs. Future work will integrate more complex biomechanical considerations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70215","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:10:29Z","timestamp":1772997029000},"page":"2076-2086","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Automated Framework for Mandibular Reconstruction: Evaluation and Clinical Application"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2359-4529","authenticated-orcid":false,"given":"Chenyao","family":"Li","sequence":"first","affiliation":[{"name":"Department of Oral Surgery, Ninth People's Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, and Shanghai Key Laboratory of Stomatology &amp; Shanghai Research Institute of Stomatology  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Guo","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Manufacturing and Life Quality Engineering, School of Mechanical Engineering Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Oral Maxillofacial &amp; Head and Neck Oncology, Shanghai Ninth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Jiao Tong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Manufacturing and Life Quality Engineering, School of Mechanical Engineering Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0408-2731","authenticated-orcid":false,"given":"Shanyong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Ninth People's Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, and Shanghai Key Laboratory of Stomatology &amp; Shanghai Research Institute of Stomatology  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23717"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844317509022776"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534\u2010199402000\u201000009"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2008.05.021"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2005.01212.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534\u2010200201000\u201000008"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/oto2.70069"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23815"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000169940.69315.9c"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/gox.0000000000004716"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999\u2010016\u20105196\u20102"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000479998.49928.71"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/prs.0b013e31828bd6b0"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000007250"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010014\u20103078\u20103"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1088\/1758\u20105090\/aa6370"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2010.06.177"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.14639\/0392\u2010100x\u2010suppl.1\u201044\u20102024\u2010n2819"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1109\/ACCESS.2025.3582504"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-78470-8"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.19723\/j.issn.1671\u2010167X.2025.01.017"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2018.00022"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbaf024"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42242\u2010021\u201000165\u20100"}],"container-title":["Head &amp; 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