{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:23:44Z","timestamp":1783164224461,"version":"3.54.6"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2022JC024"],"award-info":[{"award-number":["2022JC024"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62305190"],"award-info":[{"award-number":["62305190"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      This study aimed to evaluate whether the extent of thyroidectomy is associated with long\u2010term prognosis in patients with unilateral papillary thyroid carcinoma (PTC) and high\u2010volume (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009\u2265\u20095) central lymph node metastases (CLNM).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This study retrospectively analyzed the clinicopathological data of patients with unilateral PTC and high\u2010volume (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009\u2265\u20095) CLNM who underwent thyroidectomy between January 2013 and December 2019. Patients were divided into the thyroid lobectomy (TL) group and the total thyroidectomy (TT) group based on the extent of thyroidectomy. The primary outcome was recurrence\u2010free survival (RFS), and the secondary outcome was the incidence of postoperative complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 192 patients were included in this study. Among them, 101 patients underwent TL, whereas 91 patients underwent TT. The median follow\u2010up duration was 60\u2009months. During the follow\u2010up period, 5 cases of local recurrence were observed among 192 patients. The 5\u2010year RFS was 97.1% in the TL group and 98.8% in the TT group. The log\u2010rank test showed no significant difference in RFS between the two groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.672). However, the TT group had higher rates of transient hypoparathyroidism.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      TL does not impact the long\u2010term prognosis in unilateral PTC patients with high\u2010volume (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009\u2265\u20095) CLNM. Age\u2009\u2265\u200955 is associated with a higher risk of structure recurrence. For these patients who initially undergo TL, immediate completion thyroidectomy may not be necessary.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70217","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T14:12:04Z","timestamp":1772979124000},"page":"2057-2065","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Thyroid Lobectomy for Unilateral Papillary Thyroid Carcinoma Patients With High\u2010Volume (\n                    <scp>\n                      <i>n<\/i>\n                      \u2009\u2265\u20095\n                    <\/scp>\n                    ) Central Lymph Node Metastases"],"prefix":"10.1002","volume":"48","author":[{"given":"Guixu","family":"Lv","sequence":"first","affiliation":[{"name":"Department of Thyroid Surgery, General Surgery Qilu Hospital of Shandong University  Jinan China"},{"name":"Department of Hepatobiliary and Vascular Surgery People's Hospital Affiliated to Shandong First Medical University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, General Surgery Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9910-4159","authenticated-orcid":false,"given":"Qi","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, General Surgery Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changyuan","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, General Surgery Qilu Hospital of Shandong University  Jinan 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