{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:23:02Z","timestamp":1786123382745,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Radiofrequency ablation (RFA) is a minimally invasive alternative to thyroidectomy for select thyroid pathologies. Although international data support its safety and efficacy for small papillary thyroid carcinoma (PTC), U.S. data is limited. This study evaluates outpatient RFA outcomes for biopsy\u2010confirmed low\u2010risk PTC performed in a clinic setting with local anesthesia only.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review was conducted of adults who underwent outpatient RFA for PTC between September 2021 and February 2025. Nodules were confined to the thyroid gland without nodal or distant metastasis. Nodule volume reduction rate (VRR), thyroid function, delivered energy, and complications were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventeen RFA procedures were performed on 15 nodules. Baseline median volume and maximum diameter were 0.41\u2009mL and 1.10\u2009cm, respectively, and average VRR reached 85.3% at 12\u2009months. Two transient complications occurred, and thyroid function remained stable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Clinic\u2010performed RFA for small, low\u2010risk PTC is safe, effective, and preserves thyroid function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70246","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T07:35:20Z","timestamp":1775028920000},"page":"2355-2363","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Radiofrequency Ablation of Low\u2010Risk Primary Papillary Thyroid Carcinoma in a Clinic Setting"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4948-3496","authenticated-orcid":false,"given":"Jacob B.","family":"Green","sequence":"first","affiliation":[{"name":"Florida State University College of Medicine, Sarasota Regional Campus  Sarasota Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella C.","family":"Ihrig","sequence":"additional","affiliation":[{"name":"Kolschowsky Research and Education Institute, Sarasota Memorial Health Care System  Sarasota Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonya S.","family":"King","sequence":"additional","affiliation":[{"name":"Kolschowsky Research and Education Institute, Sarasota Memorial Health Care System  Sarasota Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4937-0171","authenticated-orcid":false,"given":"Maria G.","family":"Moreno","sequence":"additional","affiliation":[{"name":"Kolschowsky Research and Education Institute, Sarasota Memorial Health Care System  Sarasota Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Mancera","sequence":"additional","affiliation":[{"name":"Kolschowsky Research and Education Institute, Sarasota Memorial Health Care System  Sarasota Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph P.","family":"Tufano","sequence":"additional","affiliation":[{"name":"Florida State University College of Medicine, Sarasota Regional Campus  Sarasota Florida USA"},{"name":"First Physicians Group, Thyroid and Parathyroid Center, Division of Head and Neck Endocrine Surgery Sarasota Memorial Health Care System  Sarasota Florida USA"},{"name":"Brian D. Jellison Cancer Institute, Sarasota Memorial Health Care System  Sarasota Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.26348"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2025.0033"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/10507256251363120"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgad357"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2023.5202"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.14366\/usg.20112"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eprac.2022.02.011"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2016.1230893"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2024.04.010"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-024-10910-5"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jendso\/bvab110"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2024.3229"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2021.4381"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003930"},{"issue":"8","key":"e_1_2_11_16_1","first-page":"920","article-title":"Safety of Radiofrequency Ablation of Benign Thyroid Nodules and Recurrent Thyroid Cancers: A Systematic Review and Meta\u2010Analysis","volume":"33","author":"Chung S. R.","year":"2017","journal-title":"International Journal of Hyperthermia"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-07532-y"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.70246","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hed.70246","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.70246","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T14:33:41Z","timestamp":1786113221000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.70246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":16,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/hed.70246"],"URL":"https:\/\/doi.org\/10.1002\/hed.70246","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,1]]},"assertion":[{"value":"2025-11-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}