{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:18:32Z","timestamp":1780499912891,"version":"3.54.1"},"reference-count":88,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T00:00:00Z","timestamp":1777075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T00:00:00Z","timestamp":1777075200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lateral cervical ectopic thyroid gland (LETG) is rare and often difficult to distinguish from metastatic lymphadenopathy; furthermore, no standardized surgical strategy is available. This study aims to clarify the clinical features of and establish an optimized management framework for this anomaly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We present one benign LETG case and one malignant LETG case and performed a systematic literature review (2000\u20132025), yielding a pooled analysis of 69 cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The analysis revealed that a definitive pre\u2010 or intra\u2010operative diagnosis was pivotal. Malignant pathology in both the lateral neck lesion and the orthotopic thyroid gland predicted multiple surgeries (41.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007; 39%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.038). Crucially, the utilization of intraoperative frozen sections was decisive, as all patients who underwent this approach avoided a second operation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LETG management necessitates a systematic approach. Our proposed \u201cSeven\u2010Step Diagnostic Algorithm\u201d and \u201cDual\u2010Axis Treatment Strategy\u201d facilitate precise differentiation, enable a definitive single\u2010stage surgery, minimize reoperations, and guide selective preservation of the orthotopic thyroid.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70294","type":"journal-article","created":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T07:55:07Z","timestamp":1777103707000},"page":"1939-1959","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lateral Cervical Ectopic Thyroid: A Seven\u2010Step Diagnostic Algorithm and Dual\u2010Axis Treatment Strategy Derived From Case Analysis and Literature Review"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5234-068X","authenticated-orcid":false,"given":"Shuguang","family":"Huang","sequence":"first","affiliation":[{"name":"Thyroid and Breast Surgery Department, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"Thyroid and Breast Surgery Department, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejie","family":"Chen","sequence":"additional","affiliation":[{"name":"Thyroid and Breast Surgery Department, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lichuang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Thyroid and Breast Surgery Department, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9743-5489","authenticated-orcid":false,"given":"Lebin","family":"Yuan","sequence":"additional","affiliation":[{"name":"Thyroid and Breast Surgery Department, Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and Science  Xiangyang Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianrong","family":"Liu","sequence":"additional","affiliation":[{"name":"Medical College Hubei University of Arts and Science  Xiangyang Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,25]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-0461"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348947708600621"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2015.12.043"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.14310\/horm.2002.11163"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.04.037"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711020408"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100143531"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2008.23.3.548"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100120778"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.15004"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2490-6-18"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2005.0255a.x"},{"key":"e_1_2_13_14_1","article-title":"Dual Ectopic Thyroid With Normally Located Thyroid: A Case Report","volume":"2011","author":"Choudhury B. 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