{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T22:02:04Z","timestamp":1782856924200,"version":"3.54.5"},"reference-count":57,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004224","name":"Peter MacCallum Cancer Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004224","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Radiotherapy for head and neck cancer (HNC) has significant physical and emotional effects. This study investigated the feasibility of delivering \u201cPrep\u20104\u2010Radiotherapy (RT)\u201d, a multi\u2010modal, risk\u2010stratified approach to prehabilitation for people with HNC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>HNC patients planned for radiotherapy were screened for psychological distress, malnutrition, sarcopenia, dysphagia, and reduced physical function using self\u2010report measures. Low\u2010risk patients were provided access to self\u2010management resources. High\u2010risk patients were additionally referred to relevant allied health disciplines for specialist prehabilitation and provided access to self\u2010management resources. The feasibility of Prep\u20104\u2010RT was judged against a priori criteria. Primary feasibility outcomes included patient adoption (uptake: \u2265\u200970% of eligible patients consent to screening; intention to try: \u2265\u200960% of patients utilize self\u2010management resources and \u2265\u200970% of high\u2010risk patient participants verbally accept referrals to specialist prehabilitation) and fidelity (adherence to specialist pathway: \u2265\u200970% of high\u2010risk patients receive specialist prehabilitation and attend \u2265\u200970% of scheduled prehabilitation appointments).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Point estimates for four of five primary outcomes indicated acceptable feasibility. The point estimate for the fifth primary outcome, adherence as assessed by the percentage of high\u2010risk patients assigned to specialist prehabilitation who received care from required clinicians before radiotherapy, indicated feasibility with further revision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Prep\u20104\u2010RT appears to offer a feasible risk\u2010stratified program to provide prehabilitation to HNC patients prior to radiotherapy, though results for some criteria were characterized by notable missing data. Further evaluation is required to determine its effect on clinical and health service outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration Details<\/jats:title>\n                    <jats:p>ANZCTA (Australian New Zealand Clinical Trials Registry) ACTRN12623000770662.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70351","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T21:02:18Z","timestamp":1782853338000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and Acceptability of a Co\u2010Designed Model of Prehabilitation for Head and Neck Cancer Patients Undergoing Radiotherapy"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4749-6077","authenticated-orcid":false,"given":"Ella T. S.","family":"Sexton","sequence":"first","affiliation":[{"name":"Psychosocial Oncology Program Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"School of Psychology Deakin University  Burwood Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah J.","family":"Ray","sequence":"additional","affiliation":[{"name":"Nutrition and Speech Pathology Department Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6843-5076","authenticated-orcid":false,"given":"Jacqui J.","family":"Frowen","sequence":"additional","affiliation":[{"name":"Nutrition and Speech Pathology Department Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Sir Peter MacCallum Department of Oncology The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla","family":"Gough","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Medicine, Dentistry, and Health Sciences The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Poon","sequence":"additional","affiliation":[{"name":"Department of Nursing Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon P.","family":"Turnbull","sequence":"additional","affiliation":[{"name":"Consumer Representative, Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaza","family":"Abo","sequence":"additional","affiliation":[{"name":"Physiotherapy &amp; Occupational Therapy Department Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Barton","sequence":"additional","affiliation":[{"name":"Western and Central Integrated Cancer Services  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenelle M.","family":"Loeliger","sequence":"additional","affiliation":[{"name":"Nutrition and Speech Pathology Department Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Sir Peter MacCallum Department of Oncology The University of Melbourne  Melbourne Victoria Australia"},{"name":"School of Exercise and Nutrition Sciences Deakin University  Burwood Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5884-7851","authenticated-orcid":false,"given":"Maria","family":"Ftanou","sequence":"additional","affiliation":[{"name":"Psychosocial Oncology Program Peter MacCallum Cancer Centre  Melbourne Victoria Australia"},{"name":"Sir Peter MacCallum Department of Oncology The University of Melbourne  Melbourne Victoria Australia"},{"name":"School of Population and Global Health The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"issue":"11","key":"e_1_2_14_2_1","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.3390\/nu12113233","article-title":"Exercise and Nutrition Interventions in Patients With Head and Neck Cancer During Curative Treatment: A Systematic Review and Meta\u2010Analysis","volume":"12","author":"Bye A.","year":"2020","journal-title":"Nutrients"},{"issue":"6","key":"e_1_2_14_3_1","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1097\/01.mlg.0000217278.96901.fc","article-title":"Pretreatment, Preoperative Swallowing Exercises May Improve Dysphagia Quality of Life","volume":"116","author":"Kulbersh B. 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