{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:11:27Z","timestamp":1788588687419,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Head &amp;amp; Neck"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Malakoplakia is an uncommon granulomatous inflammatory disease which can mimic malignancy. Laryngopharyngeal malakoplakia associated with diabetes mellitus, hypertension, and uremia has not been previously described. There are numerous knowledge lacunae in our contemporary research on malakoplakia in patients with these comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>A 49\u2010year\u2010old male complained of mechanical dysphagia for 30\u2009days, and laryngoscopy revealed a huge mass at the base of tongue. Magnetic resonance imaging (MRI) demonstrated a lesion measured approximately 2.7\u2009\u00d7\u20092.0\u2009\u00d7\u20092.5\u2009cm. After surgery, the patient was followed up for over 20\u2009months without recurrence. IHC staining was positive for Vimentin and CD68, while SOX\u201010 and S\u2010100 were negative. Histopathological examination revealed Michaelis\u2013Gutmann bodies, confirming a diagnosis of malakoplakia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Malakoplakia should be considered in the differential diagnosis of a pharyngeal mass. Complete surgical excision could be an effective way to treat malakoplakia and patients need long\u2010term follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.70462","type":"journal-article","created":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:14:41Z","timestamp":1788585281000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laryngopharyngeal Malakoplakia Mimicking Malignancy in a Patient With Diabetes Mellitus and Uremia: A Case Report and Literature Review"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8113-4427","authenticated-orcid":false,"given":"Zilou","family":"Chen","sequence":"first","affiliation":[{"name":"Gannan Medical University  Ganzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Xiao","sequence":"additional","affiliation":[{"name":"Gannan Medical University  Ganzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9866-6585","authenticated-orcid":false,"given":"Fang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery First Affiliated Hospital of Gannan Medical University  Ganzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"issue":"2","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0022-5347(17)54940-X","article-title":"Malacoplakia: A Study of the Literature and Current Concepts of Pathogenesis, Diagnosis and Treatment","volume":"125","author":"Stanton M. 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